Introduction：Basic information about CAS 5274-63-5|Tetraethylene glycol monohexadecyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetraethylene glycol monohexadecyl ether |
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| CAS Number | 5274-63-5 | Molecular Weight | 418.65100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C24H50O5 | Melting Point | 37-38ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethanol |
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| Synonym | More Synonyms |
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Tetraethylene glycol monohexadecyl ether BiologicalActivity
| Description | Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Melting Point | 37-38ºC |
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| Molecular Formula | C24H50O5 |
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| Molecular Weight | 418.65100 |
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| Exact Mass | 418.36600 |
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| PSA | 57.15000 |
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| LogP | 5.52640 |
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| InChIKey | CACXEVGZNASLOU-UHFFFAOYSA-N |
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| SMILES | CCCCCCCCCCCCCCCCOCCOCCOCCOCCO |
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Safety Information
| Safety Phrases | 22-24/25 |
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| WGK Germany | 3 |
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| HS Code | 2909499000 |
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Customs
| HS Code | 2909499000 |
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| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| CETETH-4 |
| Tetraethylene glycol monohexadecyl ether |
| Hexadecyltetraglycol |
| C16E4 |
| C16E4,Hexadecyl tetraethylene glycol ether,Hexadecyltetraglycol |
| polyoxyethylene 4 cetyl ether |
| Hexadecyl tetraethylene glycol ether |
