CAS 3715-29-5|Sodium 3-methyl-2-oxobutanoate
| Common Name | Sodium 3-methyl-2-oxobutanoate | ||
|---|---|---|---|
| CAS Number | 3715-29-5 | Molecular Weight | 138.097 |
| Density | / | Boiling Point | 170.2ºC at 760 mmHg |
| Molecular Formula | C5H7NaO3 | Melting Point | 220-230 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | 3-Methyl-2-oxobutanoic acid, sodium salt |
|---|---|
| Synonym | More Synonyms |
Sodium 3-methyl-2-oxobutanoate BiologicalActivity
| Description | Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2]. |
| In Vivo | Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3]. |
| References | [1]. MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93. [2]. Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr;103(4):597-605. [3]. Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9;894(1):68-73. |
Chemical & Physical Properties
| Boiling Point | 170.2ºC at 760 mmHg |
|---|---|
| Melting Point | 220-230 °C (dec.)(lit.) |
| Molecular Formula | C5H7NaO3 |
| Molecular Weight | 138.097 |
| Exact Mass | 138.029282 |
| PSA | 57.20000 |
| InChIKey | WIQBZDCJCRFGKA-UHFFFAOYSA-M |
| SMILES | CC(C)C(=O)C(=O)[O-].[Na+] |
| Storage condition | Store at 0-5°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2904909090 |
Customs
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| Butanoic acid, 3-methyl-2-oxo-, sodium salt (1:1) |
| MFCD00002581 |
| EINECS 223-062-2 |
| sodium,3-methyl-2-oxobutanoate |
| Butanoic acid, 3-methyl-2-oxo-, sodium salt |
| Sodium 3-methyl-2-oxobutanoate |
| 3-Methyl-2-oxobutanoic acid |
