Introduction:Basic information about CAS 105838-14-0|N-Boc-O-tosyl hydroxylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Boc-O-tosyl hydroxylamine |
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| CAS Number | 105838-14-0 | Molecular Weight | 287.33200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C12H17NO5S | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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| Symbol | GHS07 | Signal Word | Warning |
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Names
| Name | [(2-methylpropan-2-yl)oxycarbonylamino] 4-methylbenzenesulfonate |
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| Synonym | More Synonyms |
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N-Boc-O-tosyl hydroxylamine BiologicalActivity
| Description | N-Boc-O-tosyl hydroxylamine is used as a linker for antibody-drug conjugates (ADC)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Alkyl/ether |
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| References | [1]. BOGER, Dale. CHIMER CONTAINING A TARGETING PORTION LINKED TO A SCISSION-ACTIVATED DUOCARMYCIN-TYPE PRODRUG. WO2009064913A1. |
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Chemical & Physical Properties
| Molecular Formula | C12H17NO5S |
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| Molecular Weight | 287.33200 |
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| Exact Mass | 287.08300 |
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| PSA | 93.57000 |
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| LogP | 3.42520 |
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| InChIKey | WZDPZKPHVNFUKB-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(S(=O)(=O)ONC(=O)OC(C)(C)C)cc1 |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol | GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H315-H317-H319-H335 |
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| Precautionary Statements | P261-P280-P305 + P351 + P338 |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2924299090 |
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Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles1
More Articles
| Baburaj, T.; et. al. Synlett , 1993-1996, (2011)
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Synonyms
| TERT-BUTYL TOSYLOXYCARBAMATE |
| N-Boc-O-tosyl-hydroxylamine |
| Boc N-tosyloxycarbamate |
| tert-Butyl N-Tosyloxycarbamate |