CAS 6665-86-7|7-Hydroxyflavone

Introduction：Basic information about CAS 6665-86-7|7-Hydroxyflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 7-Hydroxyflavone BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	7-Hydroxyflavone
CAS Number	6665-86-7	Molecular Weight	238.238
Density	1.3±0.1 g/cm3	Boiling Point	450.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₀O₃	Melting Point	245-247 °C(lit.)
MSDS	/	Flash Point	176.3±22.2 °C

Names

Name	7-Hydroxyflavone
Synonym	More Synonyms

7-Hydroxyflavone BiologicalActivity

Description	7-Hydroxyflavone is a flavonoid isolated from M. indica, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway[1][2].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Vinutha K, et al. Aqueous extract from Madhuca indica bark protects cells from oxidative stress caused by electron beam radiation: in vitro, in vivo and in silico approach. Heliyon. 2019 May 30;5(5):e01749. [2]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777. [3]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777.

Description

7-Hydroxyflavone is a flavonoid isolated from M. indica, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway[1][2].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. Vinutha K, et al. Aqueous extract from Madhuca indica bark protects cells from oxidative stress caused by electron beam radiation: in vitro, in vivo and in silico approach. Heliyon. 2019 May 30;5(5):e01749.

[2]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777.

[3]. Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	450.1±45.0 °C at 760 mmHg
Melting Point	245-247 °C(lit.)
Molecular Formula	C₁₅H₁₀O₃
Molecular Weight	238.238
Flash Point	176.3±22.2 °C
Exact Mass	238.062988
PSA	50.44000
LogP	3.32
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.666
InChIKey	MQGPSCMMNJKMHQ-UHFFFAOYSA-N
SMILES	O=c1cc(-c2ccccc2)oc2cc(O)ccc12

Safety Information

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
WGK Germany	3
HS Code	2914400090

Customs

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

7-hydroxy-2-phenylchromen-4-one

7-Hydroxy-2-phenyl-4H-chromen-4-one

7-Hydroxyflavone

4H-1-Benzopyran-4-one, 7-hydroxy-2-phenyl-

EINECS 229-705-3

7--Hydroxy-2-phenyl-4-benzopyrone

MFCD00006835

Recommended......