CAS 100-66-3|Anisole
Introduction：Basic information about CAS 100-66-3|Anisole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Anisole | ||
|---|---|---|---|
| CAS Number | 100-66-3 | Molecular Weight | 108.138 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 153.6±0.0 °C at 760 mmHg |
| Molecular Formula | C7H8O | Melting Point | -37 °C |
| MSDS | ChineseUSA | Flash Point | 51.7±0.0 °C |
| Symbol | GHS02 | Signal Word | Warning |
Names
| Name | anisole |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 153.6±0.0 °C at 760 mmHg |
| Melting Point | -37 °C |
| Molecular Formula | C7H8O |
| Molecular Weight | 108.138 |
| Flash Point | 51.7±0.0 °C |
| Exact Mass | 108.057518 |
| PSA | 9.23000 |
| LogP | 2.13 |
| Vapour density | 3.7 (vs air) |
| Vapour Pressure | 4.2±0.2 mmHg at 25°C |
| Index of Refraction | 1.492 |
| InChIKey | RDOXTESZEPMUJZ-UHFFFAOYSA-N |
| SMILES | COc1ccccc1 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| Water Solubility | 1.6 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Kidney, Ureter, Bladder - hematuria
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5000 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2800 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3021 mg/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 25 umol/L
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 54,133,1986 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1533 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 469 (estimated)
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 25 umol/L
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 54,133,1986 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1533 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 469 (estimated)
Safety Information
| Symbol | GHS02 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226 |
| Supplemental HS | Repeated exposure may cause skin dryness or cracking. |
| Precautionary Statements | P210-P370 + P378 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R10;R20;R38 |
| Safety Phrases | S37/39-S26-S16-S24/25 |
| RIDADR | UN 2222 3/PG 3 |
| WGK Germany | 2 |
| RTECS | BZ8050000 |
| Packaging Group | III |
| Hazard Class | 3 |
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Synonyms
| Methoxybenzene |
| Ether, methyl phenyl |
| Phenol methyl ether |
| Phenyl methyl ether |
| Phenoxymethane |
| Anizol |
| EINECS 202-876-1 |
| Anisole |
| Benzene, methoxy |
| 4-methoxybenzene |
| Methyl phenyl ether |
| MFCD00008354 |
| Benzene,methoxy |
| Anisole,AcroSeal,Extra Dry |
| Anisol |
| Benzene, methoxy- |
| methoxy benzene |
