CAS 102130-43-8|Atractyloside potassium salt

Introduction：Basic information about CAS 102130-43-8|Atractyloside potassium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Atractyloside potassium salt BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Atractyloside potassium salt
CAS Number	102130-43-8	Molecular Weight	802.987
Density	/	Boiling Point	/
Molecular Formula	C₃₀H₄₄K₂O₁₆S₂	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	atractyloside potassium salt
Synonym	More Synonyms

Atractyloside potassium salt BiologicalActivity

Description	Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Nikles S, et al. Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi). Planta Med. 2015 Aug;81(12-13):1213-20. [2]. Lemasters JJ, et al. Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting. J Biol Chem. 1979 Feb 25;254(4):1248-51. [3]. Malekova L, et al. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta. 2007 Jan;1767(1):31-44.

Description

Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Nikles S, et al. Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi). Planta Med. 2015 Aug;81(12-13):1213-20.

[2]. Lemasters JJ, et al. Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting. J Biol Chem. 1979 Feb 25;254(4):1248-51.

[3]. Malekova L, et al. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta. 2007 Jan;1767(1):31-44.

Chemical & Physical Properties

Molecular Formula	C₃₀H₄₄K₂O₁₆S₂
Molecular Weight	802.987
Exact Mass	802.134460
PSA	272.14000
LogP	3.14340
InChIKey	IUCNQFHEWLYECJ-UHFFFAOYSA-L
SMILES	C=C1C2CCC3C4(C)CC(OC5OC(CO)C(OS(=O)(=O)[O-])C(OS(=O)(=O)[O-])C5OC(=O)CC(C)C)CC(C(=O)O)C4CCC3(C2)C1O.[K+].[K+]
Storage condition	2-8°C

Safety Information

Hazard Codes	T: Toxic;
Risk Phrases	R23/24/25
Safety Phrases	S36/37
RIDADR	UN 2811 6.1/PG 2
Hazard Class	6.1(a)

Synonyms

ATRACTYLOSIDE,DIPOTASSIUM SALT,ATRACTYLIS GUMMIFERA

Atractyloside Dipotassium Salt

ATR,2K

Dipotassium (1R,4R,5R,7R,9R,10S,13R,15S)-5-carboxy-15-hydroxy-9-methyl-14-methylenetetracyclo[11.2.1.0.0]hexadec-7-yl 2-O-(3-methylbutanoyl)-3,4-di-O-sulfonato-α-D-glucopyranoside

MFCD00078810

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