CAS 37758-47-7|Ganglioside GM1
| Common Name | Ganglioside GM1 | ||
|---|---|---|---|
| CAS Number | 37758-47-7 | Molecular Weight | 1602.93000 |
| Density | 1.35 g/cm3 | Boiling Point | 1527ºC at 760 mmHg |
| Molecular Formula | C77H139N3O31 | Melting Point | 207-230ºC |
| MSDS | USA | Flash Point | 877.3ºC |
Names
| Name | ganglioside GM1 |
|---|---|
| Synonym | More Synonyms |
Ganglioside GM1 BiologicalActivity
| Description | Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. Wenchao Zhang, et al. Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review. Cell Transplant. 2019 Jun;28(6):657-661. |
Chemical & Physical Properties
| Density | 1.35 g/cm3 |
|---|---|
| Boiling Point | 1527ºC at 760 mmHg |
| Melting Point | 207-230ºC |
| Molecular Formula | C77H139N3O31 |
| Molecular Weight | 1602.93000 |
| Flash Point | 877.3ºC |
| Exact Mass | 1601.94000 |
| PSA | 540.58000 |
| LogP | 1.69070 |
| Storage condition | −20°C |
| Water Solubility | chloroform/methanol (9:1): 10 mg/mL, clear, colorless |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Risk Phrases | R22 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | FK1200000 |
| HS Code | 29400090 |
Articles52
More Articles| Methylmercury causes neuronal cell death through the suppression of the TrkA pathway: in vitro and in vivo effects of TrkA pathway activators. Toxicol. Appl. Pharmacol. 282(3) , 259-66, (2015) Methylmercury (MeHg) is an environmental toxin which induces cell death specific for the nervous systems. Here we show that MeHg causes neuronal cell death through the suppression of the tropomyosin r... | |
| Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain. J. Biol. Chem. 288(36) , 25804-9, (2013) Cholera toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells and trafficking retrograde through sorting endosomes, the trans-Golgi ... | |
| Fuzheng Huayu inhibits carbon tetrachloride-induced liver fibrosis in mice through activating hepatic NK cells. J. Ethnopharmacol. 145(1) , 175-81, (2013) Fuzheng Huayu (FZHY) is a Chinese compound herbal preparation which consists of six Chinese herbs. This study examines the preventative effects of FZHY on liver fibrosis induced by carbon tetrachlorid... |
Synonyms
| GM1 Ganglioside,Brain,Ovine-Sodium Salt) |
| Ganglioside GM1,monosialo |
| GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE |
| MFCD00466936 |
