CAS 1936-15-8|Orange G

CHEMICAL IDENTIFICATION

RTECS NUMBER :

QJ6500000

CHEMICAL NAME :

1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-(phenylazo)-, disodium salt

CAS REGISTRY NUMBER :

1936-15-8

LAST UPDATED :

199707

DATA ITEMS CITED :

17

MOLECULAR FORMULA :

C16-H10-N2-O7-S2.2Na

MOLECULAR WEIGHT :

452.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

26250 mg/kg/15W-C

TOXIC EFFECTS :

Liver - changes in liver weight Endocrine - changes in spleen weight Blood - normocytic anemia

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

27300 mg/kg/13W-C

TOXIC EFFECTS :

Blood - changes in spleen

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

136 gm/kg/13W-C

TOXIC EFFECTS :

Blood - changes in spleen

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - pig

DOSE/DURATION :

2800 mg/kg/16W-C

TOXIC EFFECTS :

Endocrine - changes in spleen weight Blood - normocytic anemia Blood - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

28 gm/kg

SEX/DURATION :

male 16 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - testes, epididymis, sperm duct

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - hamster Ovary

DOSE/DURATION :

20 umol/L/5H (Continuous)

REFERENCE :

ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,181,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,181,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2138 No. of Facilities: 613 (estimated) No. of Industries: 9 No. of Occupations: 24 No. of Employees: 11575 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2138 No. of Facilities: 588 (estimated) No. of Industries: 11 No. of Occupations: 32 No. of Employees: 27936 (estimated) No. of Female Employees: 12401 (estimated)

Talanta 78(1) , 178-86, (2009)

An automated, confirmatory and sensitive procedure has been developed and validated for the determination of Sudan (I-IV), Sudan Orange G, Sudan Red 7B and Para Red in hot chilli food samples. The pro...

Cell Res. 24(9) , 1091-107, (2014)

While the adult human heart has very limited regenerative potential, the adult zebrafish heart can fully regenerate after 20% ventricular resection. Although previous reports suggest that developmenta...

J. Hazard. Mater. 172(2-3) , 1665-70, (2009)

This work investigated the sorption performance of the ethylenediamine modified starch (CAS) for the removal of acid dyes from aqueous solutions. The influence of pH on adsorption of acid orange 10 (A...