CAS 81026-63-3|SC 34301

Introduction：Basic information about CAS 81026-63-3|SC 34301, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. SC 34301 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	SC 34301
CAS Number	81026-63-3	Molecular Weight	380.51800
Density	1.092g/cm3	Boiling Point	490.2ºC at 760 mmHg
Molecular Formula	C₂₂H₃₆O₅	Melting Point	/
MSDS	/	Flash Point	158.2ºC

Names

Name	enisoprost
Synonym	More Synonyms

SC 34301 BiologicalActivity

Description	SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].
Related Catalog	Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Prostaglandin Receptor
In Vivo	SC 34301 (200 µg/kg; p.o.; once a day for three days) 显着减少细菌移位并提高存活率[1]。 Animal Model: BALB/c mice (E. coli, burned)[1] Dosage: 200 µg/kg Administration: P.o.; once a day for three days Result: Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
References	[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5.

Chemical & Physical Properties

Density	1.092g/cm3
Boiling Point	490.2ºC at 760 mmHg
Molecular Formula	C₂₂H₃₆O₅
Molecular Weight	380.51800
Flash Point	158.2ºC
Exact Mass	380.25600
PSA	83.83000
LogP	3.72960
Index of Refraction	1.536
InChIKey	CIBHDGPIOICRGX-ZQCHCGQNSA-N
SMILES	CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCC=CCCC(=O)OC

Synonyms

Prosta-4,13-dien-1-oic acid,11,16-dihydroxy-16-methyl-9-oxo-,methyl ester,(4Z,11alpha,13E)-(+-)

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