Introduction：Basic information about CAS 86880-51-5|ICI141292, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ICI141292 |
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| CAS Number | 86880-51-5 | Molecular Weight | 369.41400 |
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| Density | 1.28g/cm3 | Boiling Point | 689.7ºC at 760mmHg |
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| Molecular Formula | C20H23N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 370.9ºC |
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Names
| Name | N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide |
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| Synonym | More Synonyms |
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ICI141292 BiologicalActivity
| Description | ICI141292 is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Cardiovascular Disease |
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| Target | β1 adrenoceptor[1] |
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| In Vitro | ICI141292 (Epanolol) is a novel anti-anginal agent which is a β1-adrenoceptor partial agonist exhibiting selective β1-adrenoceptor antagonist and selective β1-adrenoceptor agonist activity[1]. |
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| References | [1]. Hosie J, et al. Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7. |
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Chemical & Physical Properties
| Density | 1.28g/cm3 |
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| Boiling Point | 689.7ºC at 760mmHg |
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| Molecular Formula | C20H23N3O4 |
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| Molecular Weight | 369.41400 |
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| Flash Point | 370.9ºC |
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| Exact Mass | 369.16900 |
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| PSA | 114.61000 |
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| LogP | 1.73388 |
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| Index of Refraction | 1.617 |
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| InChIKey | YARKMNAWFIMDKV-UHFFFAOYSA-N |
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| SMILES | N#Cc1ccccc1OCC(O)CNCCNC(=O)Cc1ccc(O)cc1 |
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Synonyms
| Epanololum [Latin] |
| (+-)-N-(2-((3-(o-Cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-2-(p-hydroxyphenyl)acetamide |
| Visacor |
| Epanololum |
| Benzeneacetamide,N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxy |
| Epanolol |
| ICI141292 |
