CAS 102771-12-0|Nerisopam

Introduction：Basic information about CAS 102771-12-0|Nerisopam, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	Nerisopam
CAS Number	102771-12-0	Molecular Weight	309.36200
Density	1.22g/cm3	Boiling Point	475.4ºC at 760mmHg
Molecular Formula	C₁₈H₁₉N₃O₂	Melting Point	/
MSDS	/	Flash Point	241.3ºC

Names

Name	4-(7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin-1-yl)aniline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.22g/cm3
Boiling Point	475.4ºC at 760mmHg
Molecular Formula	C₁₈H₁₉N₃O₂
Molecular Weight	309.36200
Flash Point	241.3ºC
Exact Mass	309.14800
PSA	69.20000
LogP	2.50780
Vapour Pressure	3.34E-09mmHg at 25°C
Index of Refraction	1.612
InChIKey	WWQDEXGFYVSTCX-UHFFFAOYSA-N
SMILES	COc1cc2c(cc1OC)C(c1ccc(N)cc1)=NN=C(C)C2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE8746050

CHEMICAL NAME :: 5H-2,3-Benzodiazepine, 1-(4-aminophenyl)-7,8-dimethoxy-4-methyl-

CAS REGISTRY NUMBER :: 102771-12-0

LAST UPDATED :: 199706

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H19-N3-O2

MOLECULAR WEIGHT :: 309.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 128 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 108 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 275 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 182 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989

Synonyms

UNII-18Q4O339AG

Nerisopam

1-(4-Aminophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine

5H-2,3-Benzodiazepine,1-(4-aminophenyl)-7,8-dimethoxy-4-methyl

Nerisopam [INN]

1-(4-Aminophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine

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