CAS 4313-73-9|Z-Phe-Leu
| Common Name | Z-Phe-Leu | ||
|---|---|---|---|
| CAS Number | 4313-73-9 | Molecular Weight | 412.47900 |
| Density | 1.193g/cm3 | Boiling Point | 674.4ºC at 760mmHg |
| Molecular Formula | C23H28N2O5 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 361.7ºC |
Names
| Name | 4-methyl-2-[[3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoic acid |
|---|---|
| Synonym | More Synonyms |
Z-Phe-Leu BiologicalActivity
| Description | Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Makino M, et, al. Carboxypeptidase Y activity and maintenance is modulated by a large helical structure. FEBS Open Bio. 2019 Jul;9(7):1337-1343. |
Chemical & Physical Properties
| Density | 1.193g/cm3 |
|---|---|
| Boiling Point | 674.4ºC at 760mmHg |
| Molecular Formula | C23H28N2O5 |
| Molecular Weight | 412.47900 |
| Flash Point | 361.7ºC |
| Exact Mass | 412.20000 |
| PSA | 104.73000 |
| LogP | 3.92140 |
| Index of Refraction | 1.564 |
| InChIKey | IBOXOGVHBFUSFH-UHFFFAOYSA-N |
| SMILES | CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles5
More Articles| Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y. Eur. J. Biochem. 269 , 3220-3225, (2002) Cys341 of carboxypeptidase Y, which constitutes one side of the solvent-accessible surface of the S1 binding pocket, was replaced with Gly, Ser, Asp, Val, Phe or His by site-directed mutagenesis. Kine... | |
| Debittering effect of Actinomucor elegans peptidases on soybean protein hydrolysates. J. Ind. Microbiol. Biotechnol. 35 , 41-47, (2008) Effects of the enzymes in Actinomucor elegans extract and the enzyme Alcalase 2.4L on debittering the soybean protein hydrolysates were investigated. When the protein was treated only with the latter,... | |
| Characterization of a bifunctional aminoacylase/carboxypeptidase from radioresistant bacterium Deinococcus radiodurans R1. J. Biotechnol. 128 , 322-334, (2007) The gene encoding a Deinococcus radiodurans R1 bifunctional aminoacylase/carboxypeptidase (DR_ACY/CP) was amplified by polymerase chain reaction and cloned into pQE-30 to generate pQE-DRAC. The cloned... |
Synonyms
| Cbz-L-Phe-L-Leu-OH |
| Z-Phe-Leu |
| N-CBZ-Phe-Leu |
| N-Benzyloxycarbonyl-L-phenylalanyl-L-leucin |
| Z-Phe-Leu-OH |
| Cbz-Phe-Leu-OH |
