Introduction：Basic information about CAS 934628-27-0|Nilofabicin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nilofabicin |
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| CAS Number | 934628-27-0 | Molecular Weight | 340.44 |
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| Density | 1.273 g/cm3 | Boiling Point | 607.121ºC at 760 mmHg |
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| Molecular Formula | C19H20N2O2S | Melting Point | / |
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| MSDS | / | Flash Point | 320.975ºC |
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Names
| Name | 1-[(3-amino-2-methylphenyl)methyl]-4-(2-thiophen-2-ylethoxy)pyridin-2-one |
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| Synonym | More Synonyms |
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Nilofabicin BiologicalActivity
| Description | Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1]. |
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| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591–2593. |
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Chemical & Physical Properties
| Density | 1.273 g/cm3 |
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| Boiling Point | 607.121ºC at 760 mmHg |
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| Molecular Formula | C19H20N2O2S |
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| Molecular Weight | 340.44 |
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| Flash Point | 320.975ºC |
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| Exact Mass | 340.12500 |
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| PSA | 85.49000 |
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| LogP | 4.05140 |
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| InChIKey | YCLREGRRHGLOAK-UHFFFAOYSA-N |
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| SMILES | Cc1c(N)cccc1Cn1ccc(OCCc2cccs2)cc1=O |
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| Storage condition | -20°C |
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
