Introduction：Basic information about CAS 24897-50-5|Uracil-d1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Uracil-d1 |
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| CAS Number | 24897-50-5 | Molecular Weight | 112.08700 |
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| Density | 1.321g/cm3 | Boiling Point | 440.5ºC at 760mmHg |
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| Molecular Formula | C4H4N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 220.2ºC |
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Names
| Name | Uracil-5-d |
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| Synonym | More Synonyms |
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Uracil-d1 BiologicalActivity
| Description | Uracil-d1 is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2]. |
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| Related Catalog | Research Areas >>Cancer |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611. |
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Chemical & Physical Properties
| Density | 1.321g/cm3 |
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| Boiling Point | 440.5ºC at 760mmHg |
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| Molecular Formula | C4H4N2O2 |
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| Molecular Weight | 112.08700 |
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| Flash Point | 220.2ºC |
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| Exact Mass | 112.02700 |
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| PSA | 65.72000 |
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| InChIKey | ISAKRJDGNUQOIC-MICDWDOJSA-N |
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| SMILES | O=c1cc[nH]c(=O)[nH]1 |
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Synonyms
| 5-deuterio-1H-pyrimidine-2,4-dione |
| <5-2H>uracil |
| C5-deuterouracil |
| 5-Deutero-uracil |
| URACIL-5-D1 |
