CAS 29908-03-0|Ademetionine

Introduction：Basic information about CAS 29908-03-0|Ademetionine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ademetionine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	Ademetionine
CAS Number	29908-03-0	Molecular Weight	398.44
Density	/	Boiling Point	/
Molecular Formula	C₁₅H₂₂N₆O₅S	Melting Point	247-249ºC
MSDS	/	Flash Point	/

Names

Name	S-adenosyl-L-methioninate
Synonym	More Synonyms

Ademetionine BiologicalActivity

Description	Ademetionine is an intermediate metabolite of methionine. Its involvement in methylation assists in cellular growth and repair, maintains the phospho-bilipid layer in cell membranes. It also helps in the maintenance of the action of several hormones and neurotransmitters that affect mood.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological DiseaseNatural Products >>Others
References	[1]. Bressa, G.M., S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl, 1994. 154: p. 7-14. [2]. Najm, W.I., et al., S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord, 2004. 5: p. 6.

Description

Ademetionine is an intermediate metabolite of methionine. Its involvement in methylation assists in cellular growth and repair, maintains the phospho-bilipid layer in cell membranes. It also helps in the maintenance of the action of several hormones and neurotransmitters that affect mood.

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Neurological DiseaseNatural Products >>Others

References

[1]. Bressa, G.M., S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl, 1994. 154: p. 7-14.

[2]. Najm, W.I., et al., S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord, 2004. 5: p. 6.

Chemical & Physical Properties

Melting Point	247-249ºC
Molecular Formula	C₁₅H₂₂N₆O₅S
Molecular Weight	398.44
PSA	547.02000
InChIKey	MEFKEPWMEQBLKI-AIRLBKTGSA-N
SMILES	C[S+](CCC(N)C(=O)[O-])CC1OC(n2cnc3c(N)ncnc32)C(O)C1O
Storage condition	-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7334000

CHEMICAL NAME :: Adenosine, 5'-((L-3-amino-3-carboxypropyl)methylsulfonio)-5'-deo xy-, hydroxide, inner salt

CAS REGISTRY NUMBER :: 29908-03-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H22-N6-O5-S

MOLECULAR WEIGHT :: 398.49

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1S1&2YZVQ &Q &39/49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 9 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,349,1982

Safety Information

Hazard Codes	Xi
Risk Phrases	49-23-34
Safety Phrases	53-23-36/37/39-45
HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

ADEMETHIOINEDISULFATETOSYLATE

adenosylmethionine

[3H]-Ademetionine

SAM-E

EINECS 249-946-8

S-Adenosyl-L-methion

MFCD00871208

methioninyladenylate

Bis([(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl}methylsulfonium) 1,4-butanedisulfonate

S-adenosyl-L-[methyl(14)C]methionine

ADEMETIONINE

p-Toluenesulfonate salt

Ademetionin

methyl-S-adenosyl-L-Met

[14C]-Ademetionine

SAM

S-Adenosyl-L-methionine

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