CAS 372965-00-9|Diethylamine NONOate diethylammonium salt
| Common Name | Diethylamine NONOate diethylammonium salt | ||
|---|---|---|---|
| CAS Number | 372965-00-9 | Molecular Weight | 206.29 |
| Density | / | Boiling Point | / |
| Molecular Formula | C8H22N4O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | N-(diethylamino)-N-hydroxynitrous amide,N-ethylethanamine |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Sysel AM, et al. Antimicrobial properties of diethylamine NONOate, a nitric oxide donor, against Escherichia coli: a pilot study. J Antibiot (Tokyo). 2021 Apr;74(4):260-265. [2]. Du ZY, et al. The nitric oxide donor, diethylamine NONOate, enhances preservation of the donor rat heart. J Heart Lung Transplant. 1998 Nov;17(11):1113-20. |
Chemical & Physical Properties
| Molecular Formula | C8H22N4O2 |
|---|---|
| Molecular Weight | 206.29 |
| Exact Mass | 206.174271 |
| PSA | 75.58000 |
| LogP | 0.31400 |
| Storage condition | 20°C |
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H315-H318-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | C |
| Risk Phrases | 22-37/38-41 |
| Safety Phrases | 26-39 |
| RIDADR | NONH for all modes of transport |
Articles10
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| Site-specific Effects of DUOX1-Related Peroxidase on Intercellular Apoptosis Signaling. Anticancer Res. 35 , 5955-71, (2015) Intercellular apoptosis-inducing HOCl signaling is known as an interplay between superoxide anions/H₂O₂ of transformed target cells and dual oxidase 1 (DUOX1)-related peroxidase that is released from ... |
Synonyms
| 1,1-Diethyl-2-hydroxy-3-oxotriazane - N-ethylethanamine (1:1) |
| DEA NONOate DEA NO diethylammonium salt |
| Diethylamine NONOate diethylammonium salt |
| DEA/NO diethylammonium salt |
| Ethanamine, N-ethyl-, compd. with 1,1-diethyl-2-hydroxy-3-oxotriazane (1:1) |
