Introduction:Basic information about CAS 107489-37-2|Thymoctonan, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Thymoctonan |
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| CAS Number | 107489-37-2 | Molecular Weight | 918.04500 |
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| Density | 1.285g/cm3 | Boiling Point | 1331.1ºC at 760mmHg |
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| Molecular Formula | C43H67N9O13 | Melting Point | / |
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| MSDS | / | Flash Point | 758.8ºC |
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Names
| Name | (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[2-[[2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid |
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| Synonym | More Synonyms |
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Thymoctonan BiologicalActivity
| Description | Thymoctonan (THF-γ2) is the immunomodulatory octapeptide, thymic humoral factor γ2. Thymoctonan has the half-life less than 6 min at 37 °C in blood from human, rat and mouse[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Thymoctonan 形成的主要片段在人和大鼠血液中为 Glu-Asp-Gly-Pro-Lys Phe-Leu (2-8)、Asp-Gly Pro-Lys-Phe-Leu (3-8) 和 Glu-Asp Gly-Pro-Rys (2-6),在小鼠血液中为 2-8 和 2-6[1]。 |
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| References | [1]. Martignoni M, et al. Degradation of thymic humoral factor γ2 in human, rat and mouse blood: An experimental and theoretical study. Biochim Biophys Acta Proteins Proteom. 2020 Sep;1868(9):140467. |
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Chemical & Physical Properties
| Density | 1.285g/cm3 |
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| Boiling Point | 1331.1ºC at 760mmHg |
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| Molecular Formula | C43H67N9O13 |
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| Molecular Weight | 918.04500 |
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| Flash Point | 758.8ºC |
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| Exact Mass | 917.48600 |
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| PSA | 358.85000 |
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| LogP | 2.41680 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.564 |
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| InChIKey | NYJVPTKMDYSZDU-MRNVWEPHSA-N |
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| SMILES | CC(C)CC(N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)O |
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Synonyms
| THF-gamma2 |
| Thymoctonan |
| Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu |
| C43H67N9O13 |
| thymic humoral factor gamma2 |