CAS 108320-87-2|UDP-Alpha-d-n-acetylgalactosamine, disodium salt
| Common Name | UDP-Alpha-d-n-acetylgalactosamine, disodium salt | ||
|---|---|---|---|
| CAS Number | 108320-87-2 | Molecular Weight | 651.31700 |
| Density | / | Boiling Point | / |
| Molecular Formula | C17H25N3Na2O17P2 | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | disodium,[(3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate |
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| Synonym | More Synonyms |
BiologicalActivity
| Description | UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
| References | [1]. Kaundinya CR, et al. In vitro characterization of N-terminal truncated EpsC from Bacillus subtilis 168, a UDP-N-acetylglucosamine 4,6-dehydratase. Arch Biochem Biophys. 2018 Nov 1;657:78-88. [2]. Hang HC, et al. Probing glycosyltransferase activities with the Staudinger ligation. J Am Chem Soc. 2004 Jan 14;126(1):6-7. |
Chemical & Physical Properties
| Molecular Formula | C17H25N3Na2O17P2 |
|---|---|
| Molecular Weight | 651.31700 |
| Exact Mass | 651.04500 |
| PSA | 331.14000 |
| InChIKey | HXWKMJZFIJNGES-UHFFFAOYSA-L |
| SMILES | CC(=O)NC1C(OP(=O)([O-])OP(=O)([O-])OCC2OC(n3ccc(=O)[nH]c3=O)C(O)C2O)OC(CO)C(O)C1O.[Na+].[Na+] |
| Storage condition | −20°C |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles4
More Articles| Expression of the functional recombinant human glycosyltransferase GalNAcT2 in Escherichia coli. Microb. Cell Fact. 14 , 3, (2015) Recombinant protein-based therapeutics have become indispensable for the treatment of many diseases. They are produced using well-established expression systems based on bacteria, yeast, insect and ma... | |
| Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy. PLoS ONE 9(2) , e99026, (2014) Patients with IgA nephropathy (IgAN) have elevated circulating levels of IgA1 with some O-glycans consisting of galactose (Gal)-deficient N-acetylgalactosamine (GalNAc) with or without N-acetylneurami... | |
| Prediction of functional modules based on comparative genome analysis and Gene Ontology application. Nucleic Acids Res. 33 , 2822-37, (2005) We present a computational method for the prediction of functional modules encoded in microbial genomes. In this work, we have also developed a formal measure to quantify the degree of consistency bet... |
Synonyms
| UDP-N-acetylgalactosamine |
| Uridine 5'-diphospho-N-acetylgalactosamine sodium salt |
| MFCD00077894 |
| Uridine 5'-diphospho-N-acetylgalactosamine disodium salt |
| Uridine 5 inverted exclamation marka-diphospho-N-acetylgalactosamine disodium salt |
| Uridine 5'-(trihydrogen diphosphate) P'-[2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl] ester disodium salt |
| UDP-Alpha-d-n-acetylgalactosamine, disodium salt |
