Introduction：Basic information about CAS 111900-32-4|(1S,3R)-ACPD, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (1S,3R)-ACPD |
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| CAS Number | 111900-32-4 | Molecular Weight | 173.16700 |
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| Density | 1.452g/cm3 | Boiling Point | 352.7ºC at 760mmHg |
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| Molecular Formula | C7H11NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 167.1ºC |
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Names
| Name | (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid |
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| Synonym | More Synonyms |
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(1S,3R)-ACPD BiologicalActivity
| Description | (1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Neurological Disease |
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| References | [1]. A E Bandrowski, et al. Metabotropic glutamate receptors modify ionotropic glutamate responses in neocortical pyramidal cells and interneurons. Exp Brain Res. 2001 Jan;136(1):25-40. |
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Chemical & Physical Properties
| Density | 1.452g/cm3 |
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| Boiling Point | 352.7ºC at 760mmHg |
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| Molecular Formula | C7H11NO4 |
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| Molecular Weight | 173.16700 |
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| Flash Point | 167.1ºC |
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| Exact Mass | 173.06900 |
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| PSA | 100.62000 |
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| LogP | 0.35350 |
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| Vapour Pressure | 6.39E-06mmHg at 25°C |
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| Index of Refraction | 1.563 |
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| InChIKey | YFYNOWXBIBKGHB-FBCQKBJTSA-N |
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| SMILES | NC1(C(=O)O)CCC(C(=O)O)C1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- GY4060000
- CHEMICAL NAME :
- 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S-cis)-
- CAS REGISTRY NUMBER :
- 111900-32-4
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H11-N-O4
- MOLECULAR WEIGHT :
- 173.19
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
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Safety Information
| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | R20/21/22 |
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| Safety Phrases | 26-36-36/37 |
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Synonyms
| CB 1712 |
| t-ACPD |
| 1-Aminocyclopentane-1S,3R-dicarboxylic acid |
| 1S,3R-ACPD |
| 1-Amino-1,3-dicarboxycyclopentane |
| trans-ACPD |
| MFCD00153760 |
| cis-ACPD |
| trans-(1S,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid |
| 1-Amino-1,3-cyclopentanedicarboxylic acid |
