Introduction：Basic information about CAS 66966-38-9|Ethyl pyruvate-d3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ethyl pyruvate-d3 |
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| CAS Number | 66966-38-9 | Molecular Weight | 119.13400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C5H5D3O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | ethyl pyruvate (3,3,3-d3) |
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| Synonym | More Synonyms |
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Ethyl pyruvate-d3 BiologicalActivity
| Description | Ethyl pyruvate-d3 is the deuterium labeled Ethyl pyruvate[1]. Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62. [3]. Olcum M, Tufekci KU, Durur DY, et al. Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling. Antioxidants (Basel). 202110(5):745. |
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Chemical & Physical Properties
| Molecular Formula | C5H5D3O3 |
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| Molecular Weight | 119.13400 |
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| Exact Mass | 119.06600 |
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| PSA | 43.37000 |
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| LogP | 0.13850 |
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| InChIKey | XXRCUYVCPSWGCC-BMSJAHLVSA-N |
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| SMILES | CCOC(=O)C(C)=O |
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Synonyms
| Ethyl-pyruvat-d3 |
| Ethyl-pyridyl-4-ketimin |
| Ethyl-pyrid-4-yl-ketimin |
| PYRIDINE,4-PROPIONIMIDOYL |
| 3,3,3-trideuterio-2-oxo-propionic acid ethyl ester |
| 1-pyridin-4-yl-propylideneamine |
