CAS 67035-22-7|Dehydronifedipine
Introduction：Basic information about CAS 67035-22-7|Dehydronifedipine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dehydronifedipine | ||
|---|---|---|---|
| CAS Number | 67035-22-7 | Molecular Weight | 344.31900 |
| Density | 1.284g/cm3 | Boiling Point | 443.7ºC at 760 mmHg |
| Molecular Formula | C17H16N2O6 | Melting Point | 100-105ºC |
| MSDS | ChineseUSA | Flash Point | 222.1ºC |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | 2,6-Dimethyl-4-(2'-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.284g/cm3 |
|---|---|
| Boiling Point | 443.7ºC at 760 mmHg |
| Melting Point | 100-105ºC |
| Molecular Formula | C17H16N2O6 |
| Molecular Weight | 344.31900 |
| Flash Point | 222.1ºC |
| Exact Mass | 344.10100 |
| PSA | 111.31000 |
| LogP | 3.37000 |
| Appearance of Characters | powder | yellow |
| Index of Refraction | 1.575 |
| InChIKey | UMQHJQGNGLQJPF-UHFFFAOYSA-N |
| SMILES | COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+](=O)[O-] |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 + P310 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 41 |
| Safety Phrases | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
Articles11
More Articles| Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons. Mol. Pharmacol. 63(4) , 784-90, (2003) We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor kappa B (NF kappa B) in rat embryonic cultures of dopaminergic neurons. Treatment of... | |
| Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha. PLoS ONE 9(4) , e94885, (2014) Human hepatoma cell lines are commonly used as alternatives to primary hepatocytes for the study of drug metabolism in vitro. However, the phase I cytochrome P450 (CYP) enzyme activities in these cell... | |
| Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells. Drug Metab. Dispos. 42(8) , 1235-40, (2014) Humans are usually exposed to several pesticides simultaneously; consequently, combined actions between pesticides themselves or between pesticides and other chemicals need to be addressed in the risk... |
Synonyms
| dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate |
| Dehydronifedipine |
| B 4759 |
| Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate |
| Nifedipine Impurity 1 |
