CAS 53452-16-7|Vaccarin

Introduction：Basic information about CAS 53452-16-7|Vaccarin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Vaccarin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Vaccarin
CAS Number	53452-16-7	Molecular Weight	726.633
Density	1.8±0.1 g/cm3	Boiling Point	1088.1±65.0 °C at 760 mmHg
Molecular Formula	C₃₂H₃₈O₁₉	Melting Point	/
MSDS	/	Flash Point	345.6±27.8 °C

Names

Name	(1S)-1,5-Anhydro-2-O-α-L-arabinopyranosyl-1-{2-[4-(β-D-glucopyran osyloxy)phenyl]-5,7-dihydroxy-4-oxo-4H-chromen-6-yl}-D-glucitol
Synonym	More Synonyms

Vaccarin BiologicalActivity

Description	Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway[1][2].
Related Catalog	Signaling Pathways >>Epigenetics >>AMPKSignaling Pathways >>PI3K/Akt/mTOR >>AMPKResearch Areas >>Metabolic Disease
References	[1]. Lei Y, et al. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway. Eur J Pharmacol. 2019 May 15;851:13-24. [2]. Hou B,et al. Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo. Acta Cir Bras. 2020 Feb 7;34(12):e201901202.

Description

Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway[1][2].

Related Catalog

Signaling Pathways >>Epigenetics >>AMPKSignaling Pathways >>PI3K/Akt/mTOR >>AMPKResearch Areas >>Metabolic Disease

References

[1]. Lei Y, et al. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway. Eur J Pharmacol. 2019 May 15;851:13-24.

[2]. Hou B,et al. Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo. Acta Cir Bras. 2020 Feb 7;34(12):e201901202.

Chemical & Physical Properties

Density	1.8±0.1 g/cm3
Boiling Point	1088.1±65.0 °C at 760 mmHg
Molecular Formula	C₃₂H₃₈O₁₉
Molecular Weight	726.633
Flash Point	345.6±27.8 °C
Exact Mass	726.200745
PSA	319.12000
LogP	-0.74
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.762
InChIKey	GYIKGLVKALOGDP-HLEFUGOVSA-N
SMILES	O=c1cc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)cc2)oc2cc(O)c(C3OC(CO)C(O)C(O)C3OC3OCC(O)C(O)C3O)c(O)c12

Safety Information

Safety Phrases	24/25
HS Code	29389090

Synonyms

(1S)-1,5-Anhydro-2-O-α-L-arabinopyranosyl-1-{2-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4-oxo-4H-chromen-6-yl}-D-glucitol

Vaccarin

D-Glucitol, 1,5-anhydro-2-O-α-L-arabinopyranosyl-1-C-[2-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4-oxo-4H-1-benzopyran-6-yl]-, (1S)-

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