Introduction：Basic information about CAS 76296-71-4|Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. |
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| CAS Number | 76296-71-4 | Molecular Weight | 722.902 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 849.1±65.0 °C at 760 mmHg |
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| Molecular Formula | C39H62O12 | Melting Point | 189-192 °C |
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| MSDS | / | Flash Point | 467.3±34.3 °C |
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Names
| Name | (3β,25R)-Spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-g lucopyranoside |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Metabolic Enzyme/Protease >>Tyrosinase |
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| Target | IC50: 36.87 µM (tyrosinase)[1] |
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| References | [1]. Devkota KP, et, al. Tyrosinase inhibitory and antileishmanial constituents from the rhizomes of Paris polyphylla. Nat Prod Res. 2007 Apr;21(4):321-7. [2]. Singh SB, et, al. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F. Phytochemistry.1980; 21(12): 2925-2929. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 849.1±65.0 °C at 760 mmHg |
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| Melting Point | 189-192 °C |
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| Molecular Formula | C39H62O12 |
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| Molecular Weight | 722.902 |
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| Flash Point | 467.3±34.3 °C |
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| Exact Mass | 722.424133 |
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| PSA | 176.76000 |
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| LogP | 6.70 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.605 |
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| InChIKey | OJCPWEBMROBPTK-UHFFFAOYSA-N |
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| SMILES | CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OC(C)C(O)C(O)C7O)C6O)CCC5(C)C4CCC3(C)C1C2C |
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Safety Information
Synonyms
| PolyphyllinC |
| (3β,25R)-Spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside |
| β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)- |
