CAS 936091-15-5|TG-46

Introduction：Basic information about CAS 936091-15-5|TG-46, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. TG-46 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	TG-46
CAS Number	936091-15-5	Molecular Weight	510.652
Density	1.3±0.1 g/cm3	Boiling Point	687.5±65.0 °C at 760 mmHg
Molecular Formula	C₂₆H₃₄N₆O₃S	Melting Point	/
MSDS	/	Flash Point	369.6±34.3 °C

Names

Name	N-tert-butyl-3-[[5-methyl-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
Synonym	More Synonyms

TG-46 BiologicalActivity

Description	JAK-IN-35 (compound TG46) is a JAK2 inhibitor that canb be used in cancer research[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>JAK/STAT Signaling >>JAKSignaling Pathways >>Epigenetics >>JAKSignaling Pathways >>Stem Cell/Wnt >>JAK
References	[1]. Wenge Zhu, et al. Combination therapy for treating cancer. Patent WO2018187485A1.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	687.5±65.0 °C at 760 mmHg
Molecular Formula	C₂₆H₃₄N₆O₃S
Molecular Weight	510.652
Flash Point	369.6±34.3 °C
Exact Mass	510.241302
PSA	120.09000
LogP	1.83
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.621
InChIKey	MMXZBJJTHQWMEN-UHFFFAOYSA-N
SMILES	Cc1cnc(Nc2ccc(CN3CCOCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

Synonyms

EX-8668

RS0111

3-[(5-Methyl-2-{[4-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]-N-(2-methyl-2-propanyl)benzenesulfonamide

Benzenesulfonamide,N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]

Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-

N-tert-butyl-3-(5-methyl-2-(4-(morpholinomethyl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide

TG-46

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