Introduction：Basic information about CAS 22350-41-0|5,6-trans-Vitamin D3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5,6-trans-Vitamin D3 |
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| CAS Number | 22350-41-0 | Molecular Weight | 384.63800 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H44O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5,6-trans-Vitamin D3 |
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| Synonym | More Synonyms |
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5,6-trans-Vitamin D3 BiologicalActivity
| Description | 5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3[1]. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. |
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| Related Catalog | Signaling Pathways >>Vitamin D Related >>VD/VDRResearch Areas >>Metabolic Disease |
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| In Vitro | Normal human keratinocytes in the cultured human keratinocytes by determining their influence on 3H-thymidine incorporation into DNA. 5,6-trans-vitamin D3 only induces significant inhibition at 10(-6) M. The dissociation constants of vitamin D receptor (VDR) for 5,6-trans-vitamin D3 is 560 nM[1]. |
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| References | [1]. T C Chen, et al. An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3. J Nutr Biochem. 2000 May;11(5):267-72. |
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Chemical & Physical Properties
| Molecular Formula | C27H44O |
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| Molecular Weight | 384.63800 |
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| Exact Mass | 384.33900 |
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| PSA | 20.23000 |
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| LogP | 7.61900 |
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| InChIKey | QYSXJUFSXHHAJI-FVUVGDFOSA-N |
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| SMILES | C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)CCCC(C)C |
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Synonyms
| (3S,5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol |
