CAS 35790-95-5|β-Hederin
Introduction：Basic information about CAS 35790-95-5|β-Hederin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | β-Hederin | ||
|---|---|---|---|
| CAS Number | 35790-95-5 | Molecular Weight | 734.956 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 817.8±65.0 °C at 760 mmHg |
| Molecular Formula | C41H66O11 | Melting Point | 221-223ºC |
| MSDS | / | Flash Point | 240.5±27.8 °C |
Names
| Name | (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
β-Hederin BiologicalActivity
| Description | β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/Immunology |
| References | [1]. F Delmas, et al. Antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro. Planta Med. 2000 May;66(4):343-7. [2]. O Ridoux, et al. In vitro antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A(1), in association with pentamidine and amphotericin B. Phytother Res. 2001 Jun;15(4):298-301. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 817.8±65.0 °C at 760 mmHg |
| Melting Point | 221-223ºC |
| Molecular Formula | C41H66O11 |
| Molecular Weight | 734.956 |
| Flash Point | 240.5±27.8 °C |
| Exact Mass | 734.460510 |
| PSA | 175.37000 |
| LogP | 9.96 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.592 |
| InChIKey | IBAJNOZMACNWJD-HVUPOBLPSA-N |
| SMILES | CC1OC(OC2C(OC3CCC4(C)C(CCC5(C)C4CC=C4C6CC(C)(C)CCC6(C(=O)O)CCC45C)C3(C)C)OCC(O)C2O)C(O)C(O)C1O |
Synonyms
| Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-, (3β)- |
| (3β)-3-{[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}olean-12-en-28-oic acid |
