CAS 6989-21-5|Atractylon

Introduction：Basic information about CAS 6989-21-5|Atractylon, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Atractylon BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Atractylon
CAS Number	6989-21-5	Molecular Weight	216.319
Density	1.0±0.1 g/cm3	Boiling Point	287.1±19.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₀O	Melting Point	61-63℃
MSDS	/	Flash Point	121.7±8.3 °C

Names

Name	(4aS,8aR)-3,8a-Dimethyl-5-methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan
Synonym	More Synonyms

Atractylon BiologicalActivity

Description	Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].
Related Catalog	Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology
References	[1]. Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. [2]. Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68.

Description

Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].

Related Catalog

Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology

References

[1]. Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10.

[2]. Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68.

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	287.1±19.0 °C at 760 mmHg
Melting Point	61-63℃
Molecular Formula	C₁₅H₂₀O
Molecular Weight	216.319
Flash Point	121.7±8.3 °C
Exact Mass	216.151413
PSA	13.14000
LogP	5.57
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.535
InChIKey	TYPSVDGIQAOBAD-DZGCQCFKSA-N
SMILES	C=C1CCCC2(C)Cc3occ(C)c3CC12
Storage condition	2-8C

Synonyms

Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-dimethyl-5-methylene-, (4aS,8aR)-

(4aS,8aR)-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran

(4aS,8aR)-3,8a-Dimethyl-5-methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan

Atractylon

Recommended......