CAS 76376-43-7|Euphorbia factor L1

Introduction：Basic information about CAS 76376-43-7|Euphorbia factor L1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Euphorbia factor L1 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Euphorbia factor L1
CAS Number	76376-43-7	Molecular Weight	552.655
Density	1.2±0.1 g/cm3	Boiling Point	633.1±55.0 °C at 760 mmHg
Molecular Formula	C₃₂H₄₀O₈	Melting Point	/
MSDS	/	Flash Point	263.9±31.5 °C

Names

Name	5-Phosphononorvaline
Synonym	More Synonyms

Euphorbia factor L1 BiologicalActivity

Description	Euphorbia Factor L1 is a diterpenoid from Euphorbia lathyris L., reduces the expression of Bcl-2, PI3K, AKT and mTOR protein and mRNA, upregulates cleaved caspase-9 and caspase-3 levels, buts shows no effect on pro-caspase-9 and pro-caspase-3. Euphorbia Factor L1 induces apoptosis, has anticancer, antiadipogenesis, antiosteoclastogenesis and multidrug resistance-modulating effect[1].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Cardiovascular Disease
References	[1]. Zhu A, et al. Effect of euphorbia factor L1 on oxidative stress, apoptosis, and autophagy in human gastric epithelial cells. Phytomedicine. 2019 Apr 16;64:152929.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	633.1±55.0 °C at 760 mmHg
Molecular Formula	C₃₂H₄₀O₈
Molecular Weight	552.655
Flash Point	263.9±31.5 °C
Exact Mass	552.272339
PSA	108.50000
LogP	5.55
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.566
InChIKey	SDGDWRYYHQOQOJ-JGTACXIJSA-N
SMILES	CC(=O)OC1C2C(OC(=O)Cc3ccccc3)C(C)CC2(OC(C)=O)C(=O)C(C)=CC2C(CCC13CO3)C2(C)C
Storage condition	2-8°C

Synonyms

EUPATOROXIN,10-EPI

Euphorbia Factor L1

Benzeneacetic acid, (1aR,4aR,6S,7S,7aR,8S,9R,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester

(1aR,2Z,4aR,6S,7S,7aR,8R,9S,11aS)-4a,8-Diacetoxy-1,1,3,6-tetramethyl-4-oxo-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-7-yl phenylacetate

Benzeneacetic acid, (1aR,2Z,4aR,6S,7S,7aR,8R,9S,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester

(1aR,4aR,6S,7S,7aR,8S,9R,11aS)-4a,8-Diacetoxy-1,1,3,6-tetramethyl-4-oxo-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-7-yl phenylacetate

10-epi-Eupatoroxin

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