CAS 5634-42-4|2-(2-hydroxyethylamino)ethanol,2,2,3-trimethyl-3-[1-(4-methylphenyl)ethoxycarbo

Introduction：Basic information about CAS 5634-42-4|2-(2-hydroxyethylamino)ethanol,2,2,3-trimethyl-3-[1-(4-methylphenyl)ethoxycarbo, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	2-(2-hydroxyethylamino)ethanol,2,2,3-trimethyl-3-[1-(4-methylphenyl)ethoxycarbonyl]cyclopentane-1-carboxylic acid
CAS Number	5634-42-4	Molecular Weight	423.54300
Density	/	Boiling Point	427.5ºC at 760mmHg
Molecular Formula	C₂₃H₃₇NO₆	Melting Point	/
MSDS	/	Flash Point	144.9ºC

Names

Name	2-(2-hydroxyethylamino)ethanol,2,2,3-trimethyl-3-[1-(4-methylphenyl)ethoxycarbonyl]cyclopentane-1-carboxylic acid
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	427.5ºC at 760mmHg
Molecular Formula	C₂₃H₃₇NO₆
Molecular Weight	423.54300
Flash Point	144.9ºC
Exact Mass	423.26200
PSA	116.09000
LogP	3.07780
InChIKey	WSEQDEFUEFCRLT-UHFFFAOYSA-N
SMILES	Cc1ccc(C(C)OC(=O)C2(C)CCC(C(=O)O)C2(C)C)cc1.OCCNCCO

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EX1360000

CAS REGISTRY NUMBER :: 5634-42-4

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C19-H26-O4.C4-H11-N-O2

MOLECULAR WEIGHT :: 423.61

WISWESSER LINE NOTATION :: L5TJ AVOY1&R D1& A1 B1 B1 CVQ &Q2M2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2808 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 27,5121,1993

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 222,244,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,504,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,504,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9100 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - normocytic anemia

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 27,5121,1993

Synonyms

Licarbin

Syncuma

Lymethol

Hepasynthyl

Synthobilin

tocamphyl

Biliphorin

Hepatoxane

Tocanfil

Biliphorine

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