CAS 2921-57-5|Methylprednisolone succinate
| Common Name | Methylprednisolone succinate | ||
|---|---|---|---|
| CAS Number | 2921-57-5 | Molecular Weight | 474.543 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 689.6±55.0 °C at 760 mmHg |
| Molecular Formula | C26H34O8 | Melting Point | / |
| MSDS | / | Flash Point | 230.7±25.0 °C |
Names
| Name | 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid |
|---|---|
| Synonym | More Synonyms |
Methylprednisolone succinate BiologicalActivity
| Description | Methylprednisolone succinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent. |
|---|---|
| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Glucocorticoid ReceptorResearch Areas >>CancerResearch Areas >>Inflammation/Immunology |
| Target | glucocorticoid receptor[1] |
| References | [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6. [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 689.6±55.0 °C at 760 mmHg |
| Molecular Formula | C26H34O8 |
| Molecular Weight | 474.543 |
| Flash Point | 230.7±25.0 °C |
| Exact Mass | 474.225372 |
| PSA | 138.20000 |
| LogP | 2.69 |
| Vapour Pressure | 0.0±4.9 mmHg at 25°C |
| Index of Refraction | 1.593 |
| InChIKey | IMBXEJJVJRTNOW-XYMSELFBSA-N |
| SMILES | CC1CC2C(C(O)CC3(C)C2CCC3(O)C(=O)COC(=O)CCC(=O)O)C2(C)C=CC(=O)C=C12 |
| Storage condition | 2-8℃ |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2942000000 |
Customs
| HS Code | 2942000000 |
|---|
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Synonyms
| Urbason-Soluble |
| methylprednisolone 21-hemisuccinate |
| Butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester |
| MFCD00271782 |
| 4-{[(6α,11β)-11,17-Dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoic acid |
| Methylprednisolone sodium hemisuccinate |
| 6-methylprednisolone-21-hemisuccinate |
| methylprednisolone hemisuccinate esters |
| Methylprednisolone hydrogen succinate |
| Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, (6α,11β)- |
| Solumedrol |
| EINECS 220-863-9 |
| UNII-5GMR90S4KN |
| METHYLPREDNISOLONE SODIUM SUCCINATE |
| 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate) |
| Methylprednisolone hemisuccinate |
| methylprednisolone succinate |
