CAS 24880-45-3|Docosapentaenoic acid (22:5(n-3))

Introduction:Basic information about CAS 24880-45-3|Docosapentaenoic acid (22:5(n-3)), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDocosapentaenoic acid (22:5(n-3))
CAS Number24880-45-3Molecular Weight330.504
Density0.9±0.1 g/cm3Boiling Point442.2±24.0 °C at 760 mmHg
Molecular FormulaC22H34O2Melting Point/
MSDSChineseUSAFlash Point338.9±18.0 °C

Names

Name(7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid
SynonymMore Synonyms

Docosapentaenoic acid (22:5(n-3)) BiologicalActivity

DescriptionDocosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes.
Related CatalogResearch Areas >>Metabolic DiseaseNatural Products >>Others
Target

Human Endogenous Metabolite

References

[1]. Sinclair HM, et al. Essential fatty acids in perspective. Hum Nutr Clin Nutr. 1984 Jul;38(4):245-60.

Chemical & Physical Properties

Density0.9±0.1 g/cm3
Boiling Point442.2±24.0 °C at 760 mmHg
Molecular FormulaC22H34O2
Molecular Weight330.504
Flash Point338.9±18.0 °C
Exact Mass330.255890
PSA37.30000
LogP7.26
Vapour Pressure0.0±2.3 mmHg at 25°C
Index of Refraction1.509
InChIKeyYUFFSWGQGVEMMI-JLNKQSITSA-N
SMILESCCC=CCC=CCC=CCC=CCC=CCCCCCC(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JR1320000
CHEMICAL NAME :
7,10,13,16,19-Docosapentaenoic acid, (all Z)-
CAS REGISTRY NUMBER :
24880-45-3
LAST UPDATED :
199106
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H34-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
RTECSJR1320000

Articles5

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Interference by naturally occurring fatty acids in a noncellular enzyme-based aromatase bioassay.

J. Nat. Prod. 69 , 700-3, (2006)

Natural product drug discovery efforts frequently utilize noncellular screening assays. Fatty acids are commonly found in natural product extracts, and some have been shown to interfere with noncellul...

Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.

Biochem. J. 326 ( Pt 2) , 425-30, (1997)

It is now established that fatty acid 7,10,13,16-22:4 is metabolized into 4,7,10,13,16-22:5 as follows: 7,10,13,16-22:4-->9,12,15, 18-24:4-->6,9,12,15,18-24:5-->4,7,10,13,16-22:5. Neither C24 fatty ac...

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

J. Biol. Chem. 266(30) , 19995-20000, (1991)

The hypothesis that the last step in the biosynthesis of 4,7,10,13,16,19-22:6 from linolenate is catalyzed by an acyl-CoA-dependent 4-desaturase has never been evaluated by direct experimentation. Whe...

Synonyms

7,10,13,16,19-Docosapentaenoic acid, (7Z,10Z,13Z,16Z,19Z)-
(7Z,10Z,13Z,16Z,19Z)-7,10,13,16,19-Docosapentaenoic acid
all-cis-7,10,13,16,19-Docosapentaenoic acid
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID
Docosapentaenoic acid (22:5(n-3))
(7Z,10Z,13Z,16Z,19Z)-Docosa-7,10,13,16,19-pentaenoic acid
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
MFCD00156103
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