CAS 623-33-6|Glycine ethyl ester hydrochloride

Introduction：Basic information about CAS 623-33-6|Glycine ethyl ester hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Glycine ethyl ester hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles67
8. Synonyms

Common Name	Glycine ethyl ester hydrochloride
CAS Number	623-33-6	Molecular Weight	154.595
Density	1 g/cm3	Boiling Point	109.5ºC at 760 mmHg
Molecular Formula	C₄H₁₀ClNO₂	Melting Point	145-146 °C(lit.)
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS05	Signal Word	Danger

Names

Name	Glycine ethyl ester hydrochloride
Synonym	More Synonyms

Glycine ethyl ester hydrochloride BiologicalActivity

Description	Glycine ethyl ester monohydrochloride is a Glycine (HY-Y0966) derivative[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

Density	1 g/cm3
Boiling Point	109.5ºC at 760 mmHg
Melting Point	145-146 °C(lit.)
Molecular Formula	C₄H₁₀ClNO₂
Molecular Weight	154.595
Exact Mass	154.050903
PSA	52.32000
LogP	1.01050
InChIKey	TXTWXQXDMWILOF-UHFFFAOYSA-N
SMILES	CCOC(=O)CN.Cl
Storage condition	Store at RT.
Water Solubility	>1000 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC0525000

CHEMICAL NAME :: Glycine, ethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 623-33-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H9-N-O2.Cl-H

MOLECULAR WEIGHT :: 139.60

WISWESSER LINE NOTATION :: Z1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H318
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;Xi: Irritant;
Risk Phrases	R41
Safety Phrases	S26-S39-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MC0525000
HS Code	2922499990

Customs

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles67

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms.

Oncotarget 5(19) , 9118-32, (2014)

Resistance to Imatinib mesylate (IM) is an emerging problem for patients with chronic myelogenous leukemia (CML). T315I mutation in the Bcr-Abl is the predominant mechanism of the acquired resistance ...

Catalase therapy corrects oxidative stress-induced pathophysiology in incipient diabetic retinopathy.

Invest. Ophthalmol. Vis. Sci. 56 , 3095-102, (2015)

Preclinical studies have highlighted retinal oxidative stress in the pathogenesis of diabetic retinopathy. We evaluated whether a treatment designed to enhance cellular catalase reduces oxidative stre...

Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity.

J. Clin. Invest. 124(12) , 5239-48, (2014)

Heterotrimers composed of B cell CLL/lymphoma 10 (BCL10), mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), and caspase recruitment domain-containing (CARD) family adaptors p...

Synonyms

Glycine ethyl ester hydrochloride

Ethyl glycinate hydrochloride

MFCD00012871

ethyl 2-aminoacetate,hydrochloride

EINECS 210-787-4

H-Gly-OEt.HCl

H-Gly-OEt·HCl

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