Introduction：Basic information about CAS 910129-15-6|5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine |
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| CAS Number | 910129-15-6 | Molecular Weight | 359.35 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C15H22FN3O6 | Melting Point | 62-64°C |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-methylbutyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Melting Point | 62-64°C |
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| Molecular Formula | C15H22FN3O6 |
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| Molecular Weight | 359.35 |
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| Exact Mass | 359.149261 |
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| PSA | 126.40000 |
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| LogP | 0.97 |
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| Index of Refraction | 1.600 |
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| InChIKey | WBAXSXXYPPILCT-DGHYOTGBSA-N |
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| SMILES | CCC(C)COC(=O)Nc1nc(=O)n(C2OC(C)C(O)C2O)cc1F |
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| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
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Safety Information
Synonyms
| 2(1H)-Pyrimidinone, 1-(5-deoxypentofuranosyl)-5-fluoro-4-[[(pentyloxy)carbonyl]amino]- |
| unii-0jd5qg20w5 |
| 1-(5-Deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}-2(1H)-pyrimidinone |
| 1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1h)-one |
| 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine |
| Capecitabine Impurity 2 |
