Introduction：Basic information about CAS 88929-35-5|2-[(4R)-4-Hydroxy-2-oxo-1-pyrrolidinyl]acetamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-[(4R)-4-Hydroxy-2-oxo-1-pyrrolidinyl]acetamide |
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| CAS Number | 88929-35-5 | Molecular Weight | 158.16 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 494.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C6H10N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 252.9±27.3 °C |
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Names
| Name | 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-, (4S) |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | (S)-oxiracetam (S-ORC) is an inhibitor targeting apoptosis. S-ORC reduces brain infarct size and lessens neurological dysfunction in middle cerebral artery occlusion/reperfusion (MCAO/R) models. S-ORC prevents neuronal apoptosis via activating PI3K/Akt/GSK3β signaling pathway via α7 nAChR after ischemic stroke. S-ORC can prevent neuronal death after ischemic stroke[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Neurological Disease |
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| References | [1]. Fan W, et al. S-oxiracetam ameliorates ischemic stroke induced neuronal apoptosis through up-regulating α7 nAChR and PI3K / Akt / GSK3β signal pathway in rats. Neurochem Int. 2018 May;115:50-60. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 494.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C6H10N2O3 |
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| Molecular Weight | 158.16 |
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| Flash Point | 252.9±27.3 °C |
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| Exact Mass | 158.069138 |
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| PSA | 83.63000 |
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| LogP | -2.48 |
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| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
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| Index of Refraction | 1.570 |
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| InChIKey | IHLAQQPQKRMGSS-BYPYZUCNSA-N |
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| SMILES | NC(=O)CN1CC(O)CC1=O |
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Synonyms
| 1-PYRROLIDINEACETAMIDE,4-HYDROXY-2-OXO-, (4S)- |
| (S)-2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetamide |
| 2-[(4S)-4-hydroxy-2-oxopyrrolidin-1-yl]acetamide |
| S-(-)-Oxiracetam |
| oxiracetam |
| 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-, (S)- |
| (S)-Oxiracetam |
| 2-[(4R)-4-Hydroxy-2-oxo-1-pyrrolidinyl]acetamide |
| (S)-4-Hydroxy-2-oxo-1-pyrrolidineacetamide |
| 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-, (4R)- |
