Introduction：Basic information about CAS 6920-38-3|Luteolin-4'-O-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Luteolin-4'-O-glucoside |
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| CAS Number | 6920-38-3 | Molecular Weight | 448.37700 |
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| Density | 1.713g/cm3 | Boiling Point | 814.5ºC at 760 mmHg |
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| Molecular Formula | C21H20O11 | Melting Point | 210ºC (dec.) |
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| MSDS | / | Flash Point | 288.5ºC |
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Names
| Name | luteolin-4'-o-glucoside |
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| Synonym | More Synonyms |
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Luteolin-4'-O-glucoside BiologicalActivity
| Description | Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology |
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| Target | IC50: 3.7 μM (IL-5)[1] |
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| In Vitro | Luteolin-4'-O-glucoside shows cytotoxic activity against NCI-H929, U266, and OPM2 cell lines[3]. |
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| References | [1]. Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. [2]. Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. [3]. Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237. |
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Chemical & Physical Properties
| Density | 1.713g/cm3 |
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| Boiling Point | 814.5ºC at 760 mmHg |
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| Melting Point | 210ºC (dec.) |
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| Molecular Formula | C21H20O11 |
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| Molecular Weight | 448.37700 |
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| Flash Point | 288.5ºC |
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| Exact Mass | 448.10100 |
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| PSA | 190.28000 |
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| Index of Refraction | 1.74 |
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| InChIKey | UHNXUSWGOJMEFO-RQUKQETFSA-N |
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| SMILES | O=c1cc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)c(O)c2)oc2cc(O)cc(O)c12 |
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Safety Information
Synonyms
| luteolin-4'-glucoside |
| 3',4',5,7-tetrahydroxyflavone-4'-glucoside |
| MFCD00017468 |
