CAS 114902-16-8|Ciwujianoside B

Introduction：Basic information about CAS 114902-16-8|Ciwujianoside B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ciwujianoside B BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Ciwujianoside B
CAS Number	114902-16-8	Molecular Weight	1187.363
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₅₉H₉₄O₂₄	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	yemuoside YM(10)
Synonym	More Synonyms

Ciwujianoside B BiologicalActivity

Description	Ciwujianoside B is isolated from Eleutherococcus senticosus leaf, is able to penetrate and work in the brain after the oral administration. Ciwujianoside B significantly enhances object recognition memory[1].Ciwujianoside B shows radioprotective effects on the hematopoietic system in mice, which is associated with changes in the cell cycle, reduces DNA damage and down-regulates the ratio of Bax/Bcl-2 in bone marrow cells exposed to radiation[2].
Related Catalog	Signaling Pathways >>Apoptosis >>Bcl-2 FamilyResearch Areas >>Neurological Disease
References	[1]. Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain. Nutrients. 2019 May 22;11(5). pii: E1142. [2]. Li YR, et al. Comparative investigations on the protective effects of rhodioside, ciwujianoside-B and astragaloside IV on radiation injuries of the hematopoietic system in mice. Phytother Res. 2011 May;25(5):644-53.

Description

Ciwujianoside B is isolated from Eleutherococcus senticosus leaf, is able to penetrate and work in the brain after the oral administration. Ciwujianoside B significantly enhances object recognition memory[1].Ciwujianoside B shows radioprotective effects on the hematopoietic system in mice, which is associated with changes in the cell cycle, reduces DNA damage and down-regulates the ratio of Bax/Bcl-2 in bone marrow cells exposed to radiation[2].

Related Catalog

Signaling Pathways >>Apoptosis >>Bcl-2 FamilyResearch Areas >>Neurological Disease

References

[1]. Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain. Nutrients. 2019 May 22;11(5). pii: E1142.

[2]. Li YR, et al. Comparative investigations on the protective effects of rhodioside, ciwujianoside-B and astragaloside IV on radiation injuries of the hematopoietic system in mice. Phytother Res. 2011 May;25(5):644-53.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Molecular Formula	C₅₉H₉₄O₂₄
Molecular Weight	1187.363
Exact Mass	1186.613525
PSA	372.36000
LogP	7.67
Index of Refraction	1.627
InChIKey	UPROOJBJZLZCGS-CHTHVDMYSA-N
SMILES	C=C1CCC2(C(=O)OC3OC(COC4OC(CO)C(OC5OC(C)C(O)C(O)C5O)C(O)C4O)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1
Storage condition	2-8C

Synonyms

6-Deoxy-α-L-mannopyranosyl-(1->4)-2-deoxy-2-methyl-β-D-glucopyranosyl-(1->6)-1-O-{[(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-{[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-6 a,6b,9,9,12a-pentamethyl-2-methylene-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-4a(2H)-picenyl]carbonyl}-β-D-glucopyranose

β-D-Glucopyranose, O-6-deoxy-α-L-mannopyranosyl-(1->4)-O-2-deoxy-2-methyl-β-D-glucopyranosyl-(1->6)-1-O-[[(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α -L-arabinopyranosyl]oxy]-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-6a,6b,9,9,12a-pentamethyl-2-methylene-4a(2H)-picenyl]carbonyl]-

acanthopanax senticosides B

yemuoside YM10

CIWUJIANOSIDE B (RG)

Ciwujianoside B

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