Introduction：Basic information about CAS 131-12-4|Pimpinellin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pimpinellin |
|---|
| CAS Number | 131-12-4 | Molecular Weight | 246.215 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 441.0±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C13H10O5 | Melting Point | 119° |
|---|
| MSDS | / | Flash Point | 220.5±28.7 °C |
|---|
Names
| Name | 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one |
|---|
| Synonym | More Synonyms |
|---|
Pimpinellin BiologicalActivity
| Description | Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1]. |
|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
|---|
| In Vitro | Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1]. |
|---|
| References | [1]. Yang S, et al. Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes. Chem Cent J. 2013 Feb 4;7(1):24. |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 441.0±45.0 °C at 760 mmHg |
|---|
| Melting Point | 119° |
|---|
| Molecular Formula | C13H10O5 |
|---|
| Molecular Weight | 246.215 |
|---|
| Flash Point | 220.5±28.7 °C |
|---|
| Exact Mass | 246.052826 |
|---|
| PSA | 61.81000 |
|---|
| LogP | 2.06 |
|---|
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
|---|
| Index of Refraction | 1.612 |
|---|
| InChIKey | BQPRWZCEKZLBHL-UHFFFAOYSA-N |
|---|
| SMILES | COc1c(OC)c2occc2c2oc(=O)ccc12 |
|---|
| Storage condition | 2-8C |
|---|
Safety Information
Customs
| HS Code | 2932999099 |
|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| 5,6-Dimethoxy-2H-furo[2,3-h]chromen-2-one |
| 2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy- |
| 5,6-dimethoxyfuro[2,3-h]chromen-2-one |
| 4-Hydroxy-6,7-dimethoxy-5-benzofuranacrylic Acid d-Lactone |
| 5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one |
| Pimpinellin |
