CAS 107077-98-5|rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride

Introduction：Basic information about CAS 107077-98-5|rac trans-2-Phenylcyclopropylamine-d5 Hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namerac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
CAS Number107077-98-5Molecular Weight174.68200
Density/Boiling Point/
Molecular FormulaC9H7D5ClNMelting Point162-169ºC
MSDS/Flash Point/

Names

Namerac trans-2-Phenylcyclopropylamine-d5 Hydrochloride
SynonymMore Synonyms

BiologicalActivity

Description(rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].
Related CatalogSignaling Pathways >>Epigenetics >>Histone DemethylaseSignaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease
Target

Monoamine oxidase (MAO)[1] Lysine-specific demethylase 1 (LSD1)[2]

References

[1]. Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.

[2]. Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.

Chemical & Physical Properties

Melting Point162-169ºC
Molecular FormulaC9H7D5ClN
Molecular Weight174.68200
Exact Mass174.09700
PSA26.02000
LogP3.00350
InChIKeyZPEFMSTTZXJOTM-KMWRGRSGSA-N
SMILESCl.NC1CC1c1ccccc1

Safety Information

Hazard CodesXi

Synonyms

(1R,2S)-2-(2,3,4,5,6-pentadeuteriophenyl)cyclopropan-1-amine,hydrochloride
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