CAS 6294-17-3|6-chlorohexyl bromide

Introduction：Basic information about CAS 6294-17-3|6-chlorohexyl bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 6-chlorohexyl bromide BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	6-chlorohexyl bromide
CAS Number	6294-17-3	Molecular Weight	199.52
Density	1.3±0.1 g/cm3	Boiling Point	217.4±8.0 °C at 760 mmHg
Molecular Formula	C₆H₁₂BrCl	Melting Point	/
MSDS	ChineseUSA	Flash Point	101.1±0.0 °C

Names

Name	1-Bromo-6-chlorohexane
Synonym	More Synonyms

6-chlorohexyl bromide BiologicalActivity

Description	1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >>OthersSignaling Pathways >>PROTAC >>PROTAC Linker
References	[1]. Sun D, Nikonova AS, Zhang P, Deneka AY, Fitzgerald ME, Michael RE, Lee L, Lilly AC, Fisher SL, Phillips AJ, Nasveschuk CG, Proia DA, Tu Z, Golemis EA. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20(8):1367-1377.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	217.4±8.0 °C at 760 mmHg
Molecular Formula	C₆H₁₂BrCl
Molecular Weight	199.52
Flash Point	101.1±0.0 °C
Exact Mass	197.981079
LogP	3.49
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.470
InChIKey	JTYUIAOHIYZBPB-UHFFFAOYSA-N
SMILES	ClCCCCCCBr

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xn
Risk Phrases	R36/37/38
Safety Phrases	S23-S24/25
RIDADR	2810
WGK Germany	3
Packaging Group	III
Hazard Class	6.1(b)

Articles1

Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl.

Chem. Commun. (Camb.) 46(23) , 4082-4, (2010)

Alkyl bromides bearing various functional groups are smoothly converted to functionalized alkylzinc reagents by the direct insertion of magnesium in the presence of LiCl and ZnCl(2).

Synonyms

MFCD00001019

1-Bromo-6-chlorohexane

Cl(CH2)6-Br

1-Chloro-6-bromohexane

Hexane, 1-bromo-6-chloro-

1-bromo-6-chloro-hexane

6-chlorohexyl bromide

Hexyl bromide, 6-chloro-

EINECS 228-555-6

1,6-bromochlorohexane

Hexyl bromide,6-chloro

Hexane,1-bromo-6-chloro

6-Bromohexyl Chloride

1-bromo-6-chloro-n-hexane

1-bromo-6-chlorobutane

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