CAS 2909-38-8|3-Chlorophenyl isocyanate

Introduction：Basic information about CAS 2909-38-8|3-Chlorophenyl isocyanate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	3-Chlorophenyl isocyanate
CAS Number	2909-38-8	Molecular Weight	153.566
Density	1.2±0.1 g/cm3	Boiling Point	202.4±0.0 °C at 760 mmHg
Molecular Formula	C₇H₄ClNO	Melting Point	−4 °C(lit.)
MSDS	ChineseUSA	Flash Point	86.7±0.0 °C
Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Names

Name	1-chloro-3-isocyanatobenzene
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	202.4±0.0 °C at 760 mmHg
Melting Point	−4 °C(lit.)
Molecular Formula	C₇H₄ClNO
Molecular Weight	153.566
Flash Point	86.7±0.0 °C
Exact Mass	152.998138
PSA	29.43000
LogP	3.30
Vapour Pressure	0.3±0.4 mmHg at 25°C
Index of Refraction	1.551
InChIKey	HHIRBXHEYVDUAM-UHFFFAOYSA-N
SMILES	O=C=Nc1cccc(Cl)c1
Water Solubility	Decomposes

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NQ8560000

CHEMICAL NAME :: Isocyanic acid, m-chlorophenyl ester

CAS REGISTRY NUMBER :: 2909-38-8

LAST UPDATED :: 199801

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C7-H4-Cl-N-O

MOLECULAR WEIGHT :: 153.57

WISWESSER LINE NOTATION :: OCNR CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528438

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/m3/4H

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530488

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538092

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538092

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 7940 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528438

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 63 mg/m3

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 11(4),23,1967 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 ug/m3/24H/80D-C

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes in urine composition Endocrine - other changes

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 32(10),103,1967

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 ug/m3/24H/11W-C

TOXIC EFFECTS :: Liver - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - other proteins

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 32(7),3,1967 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:STEL 0.05 mg/m3 JAN 1993 OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993

Safety Information

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H314-H330-H334
Precautionary Statements	P260-P280-P284-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+:Verytoxic;
Risk Phrases	R26;R36/37/38;R42
Safety Phrases	S23-S26-S28-S36/37/39-S45-S38-S37/39-S28A-S22
RIDADR	UN 2206 6.1/PG 2
WGK Germany	2
RTECS	NQ8560000
Packaging Group	III
Hazard Class	6.1
HS Code	2929109000

Customs

HS Code	2929109000
Summary	2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

Stereochemical analogs of a muscarinic, ganglionic stimulant. cis- and trans-4-(N-(3-chlorophenyl)carbamoyloxy)-2-butenyltrimethylammonium iodides.

J. Med. Chem. 16(5) , 506-510, (1973)

Synonyms

m-Chlorfenylisokyanat [Czech]

m-chlorophenylisocyanate

Isocyanic acid,m-chlorophenyl ester

Benzene, 1-chloro-3-isocyanato-

MFCD00002016

3-Chlorophenyl isocyanate

3-Chloroisocyanatobenzene

Isocyanic Acid 3-Chlorophenyl Ester

3-Chlorophenylisocyanate

EINECS 220-822-5

1-Chloro-3-isocyanatobenzene

Benzene,1-chloro-3-isocyanato

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