CAS 50912-92-0|H-D-Arg(NO2)-Ome.HCl

Introduction：Basic information about CAS 50912-92-0|H-D-Arg(NO2)-Ome.HCl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. H-D-Arg(NO2)-Ome.HCl BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	H-D-Arg(NO2)-Ome.HCl
CAS Number	50912-92-0	Molecular Weight	269.69
Density	/	Boiling Point	410.7ºC at 760 mmHg
Molecular Formula	C₇H₁₆ClN₅O₄	Melting Point	150-160 °C
MSDS	USA	Flash Point	202.2ºC

Names

Name	methyl 2-amino-5-[[amino(nitramido)methylidene]amino]pentanoate,hydrochloride
Synonym	More Synonyms

H-D-Arg(NO2)-Ome.HCl BiologicalActivity

Description	D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide[1].
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Neurological Disease
References	[1]. Palmer RM, et, al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1251-6.

Chemical & Physical Properties

Boiling Point	410.7ºC at 760 mmHg
Melting Point	150-160 °C
Molecular Formula	C₇H₁₆ClN₅O₄
Molecular Weight	269.69
Flash Point	202.2ºC
Exact Mass	269.089081
PSA	146.05000
LogP	1.47960
InChIKey	QBNXAGZYLSRPJK-NUBCRITNSA-N
SMILES	COC(=O)C(N)CCCN=C(N)N[N+](=O)[O-].Cl
Storage condition	−20°C

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2925290090

Customs

HS Code	2925290090
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles2

Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy.

Radiology 251(3) , 697-704, (2009)

To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR) vasoreactivity and nitric oxide (NO) production in isolated microperfused DVR.Anima...

Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor.

PLoS ONE 6 , e16239, (2011)

Diabetes has been regarded as an inflammatory condition which is associated with left ventricular diastolic dysfunction (LVDD). The purpose of this study was to examine the expression levels of macrop...

Synonyms

Methyl (E)-N-[amino(nitroamino)methylene]-D-ornithinate hydrochloride (1:1)

methyl (2S)-2-amino-5-{[imino(nitroamino)methyl]amino}pentanoate,chloride

MFCD00133613

NG-nitro-L-Arg-OMe*HCl

NG-Nitro-D-arginine methyl ester hydrochloride

H-Arg(NO2)-OMe.HCl

L-NAME (hydrochloride)

D-Ornithine, N-[amino(nitroamino)methylene]-, methyl ester, (E)-, hydrochloride (1:1)

D-NAME NG-Nitro-D-arginine methyl ester hydrochloride

N5-[Imino(nitroamino)methyl]-D-ornithine methyl ester hydrochloride

H-D-Arg(NO2)-OMe HCl

H-D-Arg(NO2)-Ome.HCl

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