CAS 22748-16-9|4,4-Dimethyl-2-cyclopenten-1-one
Introduction：Basic information about CAS 22748-16-9|4,4-Dimethyl-2-cyclopenten-1-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4,4-Dimethyl-2-cyclopenten-1-one | ||
|---|---|---|---|
| CAS Number | 22748-16-9 | Molecular Weight | 110.15400 |
| Density | 0.903 | Boiling Point | 155.1ºC at 760mmHg |
| Molecular Formula | C7H10O | Melting Point | 174-175 °C |
| MSDS | ChineseUSA | Flash Point | 46ºC |
| Symbol | GHS02 | Signal Word | Warning |
Names
| Name | 4,4-dimethylcyclopent-2-en-1-one |
|---|---|
| Synonym | More Synonyms |
4,4-Dimethyl-2-cyclopenten-1-one BiologicalActivity
| Description | 4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| In Vitro | 4,4-Dimethyl-2-cyclopenten-1-one selectively kills the tumor cells (HSC-2, HL-60). 4,4-Dimethyl-2-cyclopenten-1-one exhibits CC50 (50% cytotoxic concentration) values of 43.8 μg/mL, 152 μg/mL, 118 μg/mL, 14.0 μg/mL, 177 μg/mL and 123 μg/mL in HSC-2, HSC-3, HSG, HL-60, HGF and normal cells (HPC), respectively[1]. |
| References | [1]. Tohru Nakayachi, et al. Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells. Anticancer Res. Mar-Apr 2004;24(2B):737-42. [2]. Wei-WeiZhu, et al. Cornstalk liquefaction in methanol/water mixed solvents. Fuel Processing Technology Volume 117, January 2014, Pages 1-7. |
Chemical & Physical Properties
| Density | 0.903 |
|---|---|
| Boiling Point | 155.1ºC at 760mmHg |
| Melting Point | 174-175 °C |
| Molecular Formula | C7H10O |
| Molecular Weight | 110.15400 |
| Flash Point | 46ºC |
| Exact Mass | 110.07300 |
| PSA | 17.07000 |
| LogP | 1.54160 |
| Vapour Pressure | 3.09mmHg at 25°C |
| Index of Refraction | 1.457 |
| InChIKey | YVFVCSCZJJGBAK-UHFFFAOYSA-N |
| SMILES | CC1(C)C=CC(=O)C1 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS02 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Risk Phrases | R10 |
| Safety Phrases | 16 |
| RIDADR | UN 1224 |
| Packaging Group | III |
| Hazard Class | 3.2 |
| HS Code | 2914299000 |
Customs
| HS Code | 2914299000 |
|---|---|
| Summary | 2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles2
More Articles| Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells. Anticancer Res. 24(2B) , 737-42, (2004) A series of simple alpha, beta-unsaturated carbonyl compounds (1-26) was characterized for their cytotoxic profiles against oral human normal and tumor cells. Several cycloalkenones showed potent cyto... | |
| Chemical composition of the essential oil of Tagetes minuta growing in Saudi Arabia. El-Deeb KS, et al. Saudi Pharm. J. 12(1) , 51-53, (2004) |
Synonyms
| 4,4-dimethyl-2-cyclopentenone |
| 4,4-dimethyl-2-cyclopenten-1-one |
| 4,4-dimethylcyclopent-2-enone |
| 4,4-Dimethylcyclopent-2-en-1-on |
| MFCD00075081 |
| 4,4-Dimethylcyclopent-2-ene-1-one |
