Introduction：Basic information about CAS 4627-40-1|Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI) |
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| CAS Number | 4627-40-1 | Molecular Weight | 335.24 |
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| Density | 2.11g/cm3 | Boiling Point | 462.3ºC at 760mmHg |
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| Molecular Formula | C11H12F3N5O4 | Melting Point | / |
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| MSDS | / | Flash Point | 233.4ºC |
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Names
| Name | (2R,3R,4S,5R)-2-[6-amino-2-(trifluoromethyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 2-Trifluoromethyl adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.11g/cm3 |
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| Boiling Point | 462.3ºC at 760mmHg |
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| Molecular Formula | C11H12F3N5O4 |
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| Molecular Weight | 335.24 |
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| Flash Point | 233.4ºC |
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| Exact Mass | 335.08400 |
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| PSA | 139.54000 |
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| Index of Refraction | 1.753 |
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| InChIKey | XZAXKLMYAMKNFC-UUOKFMHZSA-N |
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| SMILES | Nc1nc(C(F)(F)F)nc2c1ncn2C1OC(CO)C(O)C1O |
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Synonyms
| Adenosine,2-(trifluoromethyl)-(7CI,8CI,9CI) |
| 2-Trifluoromethyladenosine |
| 2-Trifluormethyl-adenosin |
