CAS 886-86-2|Tricaine methanesulfonate
Introduction：Basic information about CAS 886-86-2|Tricaine methanesulfonate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tricaine methanesulfonate | ||
|---|---|---|---|
| CAS Number | 886-86-2 | Molecular Weight | 261.295 |
| Density | / | Boiling Point | 305-310 |
| Molecular Formula | C10H15NO5S | Melting Point | 146-149 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 151.2ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Tricaine methanesulfonate |
|---|---|
| Synonym | More Synonyms |
Tricaine methanesulfonate BiologicalActivity
| Description | Tricaine methanesulfonate (MS-222) possesses anesthetic effect. Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| In Vitro | Tricaine methanesulfonate in powder form easily can become airborne and could become hazardous to the handler[1]. Tricaine methanesulfonate (TMS) solution is photosensitive (its color changes with light exposure), although the color change does not necessarily indicate significant activity decrease and thus color should not be used to gauge degradation[1]. |
| References | [1]. Kathleen M. Carter, et al. A review of tricaine methanesulfonate for anesthesia of fish. Reviews in Fish Biology and Fisheries volume 21, pages51–59(2011). |
Chemical & Physical Properties
| Boiling Point | 305-310 |
|---|---|
| Melting Point | 146-149 °C(lit.) |
| Molecular Formula | C10H15NO5S |
| Molecular Weight | 261.295 |
| Flash Point | 151.2ºC |
| Exact Mass | 261.067108 |
| PSA | 115.07000 |
| LogP | 2.61150 |
| InChIKey | FQZJYWMRQDKBQN-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cccc(N)c1.CS(=O)(=O)O |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03233
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic
- REFERENCE :
- PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 16,252,1974
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DG2455000 |
| HS Code | 2923900090 |
Customs
| HS Code | 2923900090 |
|---|---|
| Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| Ethyl 3-aminobenzoate methanesulfonate salt |
| Ethyl 3-aminobenzoate methanesulfonate |
| Benzoic acid, 3-amino-, ethyl ester, methanesulfonate (1:1) |
| Ethyl 3-aminobenzoate methanesulfonate (1:1) |
| Ethyl m-aminobenzoate methanesulfonate |
| ethyl 3-aminobenzoate,methanesulfonic acid |
| Benzoic acid, m-amino-, ethyl ester, methanesulfonate |
| Ethyl 3-aminobenzoate methanesulphonate salt |
| EINECS 212-956-8 |
| MFCD00013176 |
| Tricaine methansulphate |
| Tricaine mesylate |
