Introduction：Basic information about CAS 153247-40-6|Amyloid β-Protein (16-20) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Amyloid β-Protein (16-20) trifluoroacetate salt |
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| CAS Number | 153247-40-6 | Molecular Weight | 652.82 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C35H52N6O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | h-lys-leu-val-phe-phe-oh |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility)[1]. |
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| Related Catalog | Research Areas >>Neurological Disease |
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| In Vitro | β-Amyloid peptide(16-20) (-NH2) 在 1:2 摩尔比 (Aβ40/peptide) 的剂量下，共孵育 12 天后 (37 ℃)，抑制 Abeta 原纤维形成)[1]。 |
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| References | [1]. Austen BM, et al. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide. Biochemistry. 2008 Feb 19;47(7):1984-92. |
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Chemical & Physical Properties
| Molecular Formula | C35H52N6O6 |
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| Molecular Weight | 652.82 |
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| Exact Mass | 652.39500 |
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| PSA | 205.74000 |
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| LogP | 4.61820 |
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| InChIKey | SICITCLFXRGKJW-IIZANFQQSA-N |
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| SMILES | CC(C)CC(NC(=O)C(N)CCCCN)C(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O)C(C)C |
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Synonyms
