CAS 50270-33-2|Isofezolac

Introduction：Basic information about CAS 50270-33-2|Isofezolac, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Isofezolac BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Isofezolac
CAS Number	50270-33-2	Molecular Weight	354.40100
Density	1.18g/cm3	Boiling Point	542.8ºC at 760 mmHg
Molecular Formula	C₂₃H₁₈N₂O₂	Melting Point	/
MSDS	/	Flash Point	282.1ºC

Names

Name	2-(2,4,5-triphenylpyrazol-3-yl)acetic acid
Synonym	More Synonyms

Isofezolac BiologicalActivity

Description	Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties[1][2].
Related Catalog	Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>PGE synthase
References	[1]. J Mizoule, et al. Study of two new non-steroid anti-inflammatory drugs having a pyrazole structure (LM 22070 and LM 22102). Arch Int Pharmacodyn Ther. 1979 Apr;238(2):305-32. [2]. I Rocher, et al. The effect of antacid and aspirin on the bioavailability of isofezolac in man. Int J Clin Pharmacol Ther Toxicol. 1984 Sep;22(9):464-9.

Description

Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties[1][2].

Related Catalog

Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>PGE synthase

References

[1]. J Mizoule, et al. Study of two new non-steroid anti-inflammatory drugs having a pyrazole structure (LM 22070 and LM 22102). Arch Int Pharmacodyn Ther. 1979 Apr;238(2):305-32.

[2]. I Rocher, et al. The effect of antacid and aspirin on the bioavailability of isofezolac in man. Int J Clin Pharmacol Ther Toxicol. 1984 Sep;22(9):464-9.

Chemical & Physical Properties

Density	1.18g/cm3
Boiling Point	542.8ºC at 760 mmHg
Molecular Formula	C₂₃H₁₈N₂O₂
Molecular Weight	354.40100
Flash Point	282.1ºC
Exact Mass	354.13700
PSA	55.12000
LogP	4.83340
Index of Refraction	1.635
InChIKey	LZRDDINFIHUVCX-UHFFFAOYSA-N
SMILES	O=C(O)Cc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1

Safety Information

HS Code	2933199090

Customs

HS Code	2933199090
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Isofezolacum [INN-Latin]

Isofezolacum

Isofezolaco [INN-Spanish]

(2,4,5-triphenyl-2H-pyrazol-3-yl)-acetic acid

1,3,4-triphenyl-1h-pyrazole-5-acetic acid

1,3,4-Triphenyl-5-pyrazolessigsaeure

Isofezolaco

1,3,4-triphenyl-5-pyrazolylacetic acid

Isofezolac

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