CAS 6211-15-0|morphine sulfate pentahydrate
Introduction：Basic information about CAS 6211-15-0|morphine sulfate pentahydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | morphine sulfate pentahydrate | ||
|---|---|---|---|
| CAS Number | 6211-15-0 | Molecular Weight | 758.83000 |
| Density | / | Boiling Point | 476.2ºC at 760 mmHg |
| Molecular Formula | C34H50N2O15S | Melting Point | >240ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 241.8ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | morphine sulfate pentahydrate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Boiling Point | 476.2ºC at 760 mmHg |
|---|---|
| Melting Point | >240ºC (dec.) |
| Molecular Formula | C34H50N2O15S |
| Molecular Weight | 758.83000 |
| Flash Point | 241.8ºC |
| Exact Mass | 758.29300 |
| PSA | 234.99000 |
| LogP | 2.37850 |
| InChIKey | GRVOTVYEFDAHCL-RTSZDRIGSA-N |
| SMILES | CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5.CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5.O.O.O.O.O.O=S(=O)(O)O |
| Storage condition | Controlled Substance, -20°C Freezer |
| Water Solubility | ethanol: 1.8 mg/mL |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 973 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,228,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,228,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7173 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| Safety Phrases | 22-36 |
| RIDADR | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | QC8760000 |
Articles112
More Articles| Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. J. Pharmacol. Exp. Ther. 352(3) , 462-70, (2015) Morphine is metabolized in humans to morphine-3-glucuronide (M3G) and the pharmacologically active morphine-6-glucuronide (M6G). The hepatobiliary disposition of both metabolites relies upon multidrug... | |
| Catalytic enantioselective synthesis of quaternary carbon stereocentres. Nature 516(7530) , 181-91, (2014) Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catal... | |
| Enteral absorption and haemodynamic response of clonidine in infants post-cardiac surgery. Br. J. Anaesth. 113(6) , 964-9, (2014) Clonidine is a useful analgesic-sedative agent; however, few data exist regarding its use in infants after congenital heart disease surgery. We thus aimed to assess the absorption and safety of entera... |
Synonyms
| levo-morphine sulfate |
| Kadian (tn) |
| (-)-morphine sulfate |
| Astramor ph (tn) |
| morphin sulfate |
| Morphine sulfate hydrate |
| Depodur (tn) |
| MORPHINESULFATE,USP |
| Depodur |
| morphine sulphate |
| Astramor ph |
| Avinza (tn) |
| Morphia Sulfate Hydrate |
