CAS 68617-64-1|3-(2-Pyridyldithio)propanoic Acid

Introduction：Basic information about CAS 68617-64-1|3-(2-Pyridyldithio)propanoic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 3-(2-Pyridyldithio)propanoic Acid BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	3-(2-Pyridyldithio)propanoic Acid
CAS Number	68617-64-1	Molecular Weight	215.29300
Density	/	Boiling Point	/
Molecular Formula	C₈H₉NO₂S₂	Melting Point	68-71C
MSDS	/	Flash Point	/

Names

Name	3-(pyridin-2-yldisulfanyl)propanoic acid
Synonym	More Synonyms

3-(2-Pyridyldithio)propanoic Acid BiologicalActivity

Description	3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Melting Point	68-71C
Molecular Formula	C₈H₉NO₂S₂
Molecular Weight	215.29300
Exact Mass	215.00700
PSA	100.79000
LogP	2.29660
InChIKey	DJBRKGZFUXKLKO-UHFFFAOYSA-N
SMILES	O=C(O)CCSSc1ccccn1
Storage condition	-20°C

Synonyms

2-carboxyethyl-pyridin-2-yldisulphide

3-(2-Pyridinyldithio)propanoic Acid

3-(2-Pyridyldithio)propanoic acid

Propanoic acid,3-(2-pyridinyldithio)

2-Carboxyethyl 2-Pyridyl Disulfide

3-(PYRIDIN-2-YLDITHIO)PROPANOIC ACID

3-(2-pyridinyldisulfanyl)propanoic acid

3-(pyridin-2-yldithio)-propionic acid

3-(2-Pyridyldithio)propionic acid

3-(pyridin-2-yldisulfanyl)propionic acid

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