CAS 56-45-1|L-serine
Introduction：Basic information about CAS 56-45-1|L-serine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-serine | ||
|---|---|---|---|
| CAS Number | 56-45-1 | Molecular Weight | 105.093 |
| Density | 1.6 | Boiling Point | 394.8±32.0 °C at 760 mmHg |
| Molecular Formula | C3H7NO3 | Melting Point | 222ºC |
| MSDS | ChineseUSA | Flash Point | 192.6±25.1 °C |
Names
| Name | L-serine |
|---|---|
| Synonym | More Synonyms |
L-serine BiologicalActivity
| Description | L-Serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation. |
|---|---|
| Related Catalog | Research Areas >>CancerNatural Products >>Others |
| Target | Human Endogenous Metabolite |
| In Vitro | L-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. In cell cultures, L-Serine is a conditional essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization.L-Serine and the products of its metabolism have been recognized not only to be essential for cell proliferation, but also to be necessary for specific functions in the central nervous system[1]. |
| References | [1]. de Koning TJ, et al. L-Serine in disease and development. Biochem J. 2003 May 1;371(Pt 3):653-61. |
Chemical & Physical Properties
| Density | 1.6 |
|---|---|
| Boiling Point | 394.8±32.0 °C at 760 mmHg |
| Melting Point | 222ºC |
| Molecular Formula | C3H7NO3 |
| Molecular Weight | 105.093 |
| Flash Point | 192.6±25.1 °C |
| Exact Mass | 105.042595 |
| PSA | 83.55000 |
| LogP | -1.58 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.519 |
| InChIKey | MTCFGRXMJLQNBG-REOHCLBHSA-N |
| SMILES | NC(CO)C(=O)O |
| Storage condition | 2~8℃ |
| Water Solubility | 250 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,279,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81867 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81867 No. of Facilities: 305 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 5855 (estimated) No. of Female Employees: 4144 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,279,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81867 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81867 No. of Facilities: 305 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 5855 (estimated) No. of Female Employees: 4144 (estimated)
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VT8100000 |
| HS Code | 29225000 |
Customs
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| L-Serin |
| (2R)-2-amino-3-hydroxypropanoic acid |
| Ser |
| S-serine |
| (S)-2-Amino-3-hydroxypropionic acid |
| SERINE,USP |
| Serine |
| SERINE,L |
| (2R)-2-Amino-3-hydroxypropionic acid |
| H-D-Ser-OH |
| L-3-Hydroxy-2-aminopropionic acid |
| (S)-a-Amino-b-hydroxypropionic acid |
| (S)-2-amino-3-hydroxypropanoic acid |
| Propanoic acid, 2-amino-3-hydroxy-, (S)- |
| H-Ser-OH |
| H-L-SER-OH |
| (S)-2-amino-3-hydroxy-Propanoic acid |
| 2-Amino-3-hydroxypropanoic acid, (S)- |
| (R)-(-)-Serine |
| d-ser |
| Serine, D- |
| D-Serine |
| Serine, L- |
| (S)-(-)-serine |
| .α.-Amino-.β.-hydroxypropionic acid |
| L-2-Amino-3-hydroxypropionic acid |
| (-)-Serine |
| L-Serine |
| (R)-Serine |
| 3-hydroxy-L-Alanine |
| L-Ser |
| EINECS 200-274-3 |
| MFCD00064224 |
| b-Hydroxy-L-alanine |
