CAS 55750-63-5|N-Succinimidyl 6-maleimidohexanoate
| Common Name | N-Succinimidyl 6-maleimidohexanoate | ||
|---|---|---|---|
| CAS Number | 55750-63-5 | Molecular Weight | 308.287 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 480.6±47.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O6 | Melting Point | 70-73 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 244.5±29.3 °C |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | N-Succinimidyl 6-maleimidohexanoate |
|---|---|
| Synonym | More Synonyms |
N-Succinimidyl 6-maleimidohexanoate BiologicalActivity
| Description | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. |
|---|---|
| Related Catalog | Signaling Pathways >>Antibody-drug Conjugate >>ADC LinkerResearch Areas >>Cancer |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.6±47.0 °C at 760 mmHg |
| Melting Point | 70-73 °C(lit.) |
| Molecular Formula | C14H16N2O6 |
| Molecular Weight | 308.287 |
| Flash Point | 244.5±29.3 °C |
| Exact Mass | 308.100830 |
| PSA | 101.06000 |
| LogP | -0.81 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.577 |
| InChIKey | VLARLSIGSPVYHX-UHFFFAOYSA-N |
| SMILES | O=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O |
| Storage condition | −20°C |
| Water Solubility | chloroform: 100mg/mL |
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H351 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
Customs
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles14
More Articles| Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor. J. Bacteriol. 197 , 3110-20, (2015) A number of investigations of Escherichia coli have suggested that the DNA-binding protein H-NS, in addition to its well-known functions in chromosome organization and gene regulation, interacts direc... | |
| Successful acquisition of a neutralizing monoclonal antibody against a novel neutrophil-activating peptide, mitocryptide-1. Biochem. Biophys. Res. Commun. 463 , 54-9, (2015) Mitocryptide-1 (MCT-1) is a novel neutrophil-activating peptide derived from mitochondrial cytochrome c oxidase subunit VIII, and its physiological role and involvement in various diseases have not ye... | |
| Moderate PEGylation of the carrier protein improves the polysaccharide-specific immunogenicity of meningococcal group A polysaccharide conjugate vaccine. Vaccine 33 , 3208-14, (2015) Neisseria meningitidis can cause severe and fulminant diseases such as meningitis. Meningococcal capsular polysaccharide (PS) is a key virulence determinant that is not able to induce immunological me... |
Synonyms
| 1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione |
| MFCD00043043 |
| 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione |
| 1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]- |
| (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate |
| N-succinimidyl-6-maleimidocaproate |
| 6-Maleimidohexanoic acid N-hydroxysuccinimide ester |
| MCOSU |
| EMCS |
