CAS 55750-63-5|N-Succinimidyl 6-maleimidohexanoate

Introduction:Basic information about CAS 55750-63-5|N-Succinimidyl 6-maleimidohexanoate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-Succinimidyl 6-maleimidohexanoate
CAS Number55750-63-5Molecular Weight308.287
Density1.4±0.1 g/cm3Boiling Point480.6±47.0 °C at 760 mmHg
Molecular FormulaC14H16N2O6Melting Point70-73 °C(lit.)
MSDSChineseUSAFlash Point244.5±29.3 °C
Symbol
GHS07, GHS08
Signal WordWarning

Names

NameN-Succinimidyl 6-maleimidohexanoate
SynonymMore Synonyms

N-Succinimidyl 6-maleimidohexanoate BiologicalActivity

Description6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.
Related CatalogSignaling Pathways >>Antibody-drug Conjugate >>ADC LinkerResearch Areas >>Cancer

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point480.6±47.0 °C at 760 mmHg
Melting Point70-73 °C(lit.)
Molecular FormulaC14H16N2O6
Molecular Weight308.287
Flash Point244.5±29.3 °C
Exact Mass308.100830
PSA101.06000
LogP-0.81
Vapour Pressure0.0±1.2 mmHg at 25°C
Index of Refraction1.577
InChIKeyVLARLSIGSPVYHX-UHFFFAOYSA-N
SMILESO=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O
Storage condition−20°C
Water Solubilitychloroform: 100mg/mL

Safety Information

Symbol
GHS07, GHS08
Signal WordWarning
Hazard StatementsH315-H319-H335-H351
Precautionary StatementsP280-P305 + P351 + P338-P337 + P313
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn: Harmful;Xi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36/37-S36
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2925190090

Customs

HS Code2925190090
Summary2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles14

More Articles
Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor.

J. Bacteriol. 197 , 3110-20, (2015)

A number of investigations of Escherichia coli have suggested that the DNA-binding protein H-NS, in addition to its well-known functions in chromosome organization and gene regulation, interacts direc...

Successful acquisition of a neutralizing monoclonal antibody against a novel neutrophil-activating peptide, mitocryptide-1.

Biochem. Biophys. Res. Commun. 463 , 54-9, (2015)

Mitocryptide-1 (MCT-1) is a novel neutrophil-activating peptide derived from mitochondrial cytochrome c oxidase subunit VIII, and its physiological role and involvement in various diseases have not ye...

Moderate PEGylation of the carrier protein improves the polysaccharide-specific immunogenicity of meningococcal group A polysaccharide conjugate vaccine.

Vaccine 33 , 3208-14, (2015)

Neisseria meningitidis can cause severe and fulminant diseases such as meningitis. Meningococcal capsular polysaccharide (PS) is a key virulence determinant that is not able to induce immunological me...

Synonyms

1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
MFCD00043043
1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-
(2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
N-succinimidyl-6-maleimidocaproate
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
MCOSU
EMCS
CAS 87981-04-2|Maleimide-C10-NHS ester
CAS 102185-50-2|Bromophenol Red sodium salt
Recommended......
TOP